Table 1

Patients characteristics (n=1065)

Clinical data
 Age, years71±13
 Male gender, %58
 Height, cm165±10
 Weight, kg75±16
 Body surface area, m21.8±0.2
 Body mass index, kg/m227±5
 Symptoms (n=919), %77
 History of hypertension, %72
 Systolic blood pressure, mm Hg132±22
 Diastolic blood pressure, mm Hg72±11
 Diabetes, %27
 Coronary artery disease, %57
 Prior myocardial infarction, %31
 Atrial fibrillation, %8
 Chronic obstructive pulmonary disease, %21
 Renal failure, %18
 Logistic EuroSCORE, %7.1 (3.7–14.9)
Doppler echocardiographic data
Standard echo variables
 Bicuspid aortic valve, %27
 LV outflow tract diameter, cm2.1±0.2
 Stroke volume index, mL/m239±9
 Peak aortic jet velocity, m/s3.3±0.9
 Mean transvalvular gradient, mm Hg27±16
 Aortic valve area, cm21.00±0.31
 Aortic valve area index, cm2/m20.56±0.18
 Energy loss index, cm2/m20.65±0.24
 Dimensionless velocity index0.29±0.09
 Aortic regurgitation grade1 (0–1)
 Mitral regurgitation grade1 (0–2)
 Tricuspid regurgitation grade1 (0–2)
 LV ejection fraction, %60±14
 LV end-diastolic diameter, cm4.8±0.7
 LV end-systolic diameter, cm3.0±0.8
 LV end-diastolic volume, mL111±36
 Valvuloarterial impedance, mm Hg/mL m24.2±1.2
Prevalence of patients according to threshold values defined by guidelines
 Stroke volume index <35 mL/m2, %34
 Peak aortic jet velocity >4 m/s, %22
 Mean transvalvular gradient >40 mm Hg, %19
 Aortic valve area <1 cm2, %51
 Aortic valve area index <0.6 cm2/m2, %62
 Energy loss index <0.6 cm2/m2, %46
 Dimensionless velocity index <0.25, %41
 LV ejection fraction <50%, %17
 Valvuloarterial impedance >4.5, %35
  • Values are mean±SD or median (IQR).

  • LV, left ventricle.