Example search strategy and inclusion/exclusion criteria
| HFPEF search strategy for Ovid MEDLINE(R) |
|---|
| 1. Heart failure 2. Normal ejection fraction 3. Preserved cardiac function 4. Preserved ejection fraction 5. 1 and 2 6. 1 and 3 7. 1 and 4 8. Diastolic heart failure 9. Diastolic dysfunction 10. HFPEF 11. HFNEF 12. or/5–11 |
| Inclusion criteria |
| 1. Randomised controlled trial 2. Trial inclusion criteria specifying heart failure signs and symptoms, left ventricular ejection fraction >40% 3. Pharmacological intervention with placebo or other pharmacological comparison 4. Outcomes including all-cause and cardiovascular mortality, hospitalisation, changes in NYHA class, exercise capacity (6-min walking distance, VO2Max) or quality of life |
| Exclusion criteria |
| 1. Non-English language 2. Abstracts or conference publication 3. Unpublished studies 4. Healthy controls |