Preintervention and postintervention period results of cardiovascular risk assessments by diet allocation
| Low polyphenol (n=47) | Change | Within-group p value | High polyphenol (n=46) | Change | Within-group p value | Between-group p value | |||
|---|---|---|---|---|---|---|---|---|---|
| Pre | Post | Pre | Post | ||||||
| Max response to acetylcholine, infused:non-infused (%)*† | 123.9 (99.6) | 136.7 (143.7) | 12.8 (−34.8 to 60.4) | 0.590 | 109.1 (84.7) | 225.0 (180.4) | 115.9 (70.1 to 161.6) | <0.001 | 0.02 |
| Max response to sodium nitroprusside, infused:non-infused (%)*† | 126.3 (120.4) | 106.5 (87.7) | −19.7 (−59.9 to 18.4) | 0.303 | 107.7 (70.1) | 120.2 (92.5) | 12.5 (−14.7 to 39.7) | 0.358 | 0.169 |
| Systolic blood pressure (mm Hg)* | 141.7 (9.3) | 136.9 (10.6) | −4.83 (−7.38 to 2.28) | <0.001 | 140.6 (8.9) | 131.6 (12.5) | −9.06 (−12.8 to −5.40) | <0.001 | 0.059 |
| Diastolic blood pressure (mm Hg)* | 85.5 (6.9) | 82.0 (6.1) | −3.53 (−5.24 to −1.82) | <0.001 | 84.5 (7.6) | 79.1 (8.2) | −5.35 (−7.81 to −2.88) | <0.001 | 0.227 |
| Body mass index (kg/m2)* | 29.8 (5.0) | 29.8 (5.0) | 0.01 (−0.10 to 0.12) | 0.842 | 31.6 (6.3) | 31.6 (6.5) | −0.01 (−0.24 to 0.23) | 0.961 | 0.897 |
| Total cholesterol (mmol/L)* | 5.2 (1.2) | 5.3 (1.1) | 0.10 (−0.08 to 0.28) | 0.250 | 5.8 (1.3) | 5.6 (1.0) | −0.21 (−0.57 to 0.04) | 0.097 | 0.042 |
| High-density lipoprotein (mmol/L)* | 1.4 (0.4) | 1.4 (0.3) | 0.01 (−0.03 to 0.05) | 0.725 | 1.4 (0.4) | 1.5 (0.4) | 0.02 (−0.03 to 0.06) | 0.482 | 0.753 |
| Low-density lipoprotein (mmol/L)* | 4.2 (1.3) | 4.3 (1.2) | 0.08 (−0.10 to 0.26) | 0.366 | 4.7 (1.4) | 4.5 (1.0) | −0.25 (−0.57 to 0.06) | 0.109 | 0.063 |
| Triglycerides (mmol/L)T | 1.6 (1.0, 2.32) | 1.5 (1.1, 2.4) | 0.97 (0.90 to 1.05) | 0.470 | 1.6 (1.1, 2.1) | 1.6 (1.1, 2.3) | 0.99 (0.89 to 1.10) | 0.825 | 0.807 |
Bold figures signify significant p values.
*Normally distributed variables at baseline were summarised as mean (SD). Within-group change assessed using paired samples t test and between-group differences in change assessed using independent samples t test. Change expressed as mean difference (95% CI).
‡Based on 92 subjects due to missing microvascular function data on one patient in low-polyphenol group.
†Skewed variables were logarithmically transformed and baseline values summarised as geometric mean (IQR). Within-group change assessed using paired samples t test and between-group differences in change assessed using independent samples t test. Change expressed as geometric mean (95% CI), which, due to the logarithmic transformation, represents the ratio of the post to pre value.