Table 3

Predictive ability of modifications to the GRACE score in patients with COPD

Method for obtaining predicted risk of deathM-H pooled RR (95% CI) for death at 6 months adjusted for predicted risk of deathC-statisticsHosmer–Lemeshow p value
Normal GRACE score (comparator for 1)1.29 (1.28 to 1.33)0.8166>0.999
1. Normal GRACE score—multiply risk of death by 1.3 for patients with COPD0.99 (0.96 to 1.01)0.8181 (p<0.001)*>0.999
MINAP-derived GRACE score (comparator for 2–3)1.23 (1.20 to 1.26)0.8322>0.999
2. MINAP-derived GRACE score+smoking1.20 (1.17 to 1.23)0.8323 (p=0.274)*>0.999
3. MINAP-derived GRACE score+COPD1.00 (0.94 to 1.02)0.8333 (p<0.001)*>0.999
  • *p Values compare the C-statistics for the modified models with either the normal GRACE score or the MINAP-derived GRACE score.

  • COPD, chronic obstructive pulmonary disease; GRACE, Global Registry of Acute Coronary Events; MINAP, Myocardial Ischaemia National Audit Project.