Table 2

Anatomic and haemodynamic determinants of WSS

Parameter	β	95% CI	p Value
Resting
Peak PG, per 1 mm Hg/cm	1.281	0.348 to 2.215	0.007
Blood flow, per 1 mL/min	0.683	0.344 to 1.021	<0.001
Distance from LM ostium, per 1 mm	−0.298	−0.556 to −0.039	0.024
MLA, per 0.1 mm²	−1.676	−2.435 to −0.917	<0.001
Lesion length, per 1 mm	−1.157	−1.805 to −0.510	<0.001
Hyperaemic
Peak PG, per 1 mm Hg/cm	0.643	0.068 to 1.219	0.028
Blood flow, per 1 mL/min	0.881	0.520 to 1.242	<0.001
Distance from LM ostium, per 1 mm	−1.882	−3.053 to −0.711	0.002
MLA, per 0.1 mm²	−6.998	−9.222 to −4.774	<0.001
Lesion length, per 1 mm	−4.200	−5.994 to −2.406	<0.001

Multivariate analyses were performed with the variables presented in table 2.
LM, left main coronary artery; MLA, minimal lumen area; PG, pressure gradient WSS, wall shear stress.