Incremental value of WSS over luminal narrowing for assessing adverse plaque characteristics
| AUC | Category-free NRI | IDI | ||||
|---|---|---|---|---|---|---|
| Value | p Value | Value | p Value | Value | p Value | |
| Any of high-risk features | ||||||
| % DS (reference)* | 0.540 | – | – | – | – | – |
| % DS+WSS | 0.718 | 0.031 | 0.827 | <0.001 | 0.131 | <0.001 |
| Low-plaque density | ||||||
| % DS (reference)* | 0.558 | – | – | – | – | – |
| % DS+WSS | 0.689 | 0.075 | 0.508 | 0.034 | 0.093 | 0.018 |
| Positive remodelling | ||||||
| % DS (reference)* | 0.576 | – | – | – | – | – |
| % DS+WSS | 0.706 | 0.077 | 0.688 | <0.001 | 0.112 | 0.002 |
| Napkin-ring sign | ||||||
| % DS (reference)* | 0.639 | – | – | – | – | – |
| % DS+WSS | 0.808 | <0.001 | 0.759 | 0.002 | 0.215 | <0.001 |
| Spotty calcification | ||||||
| % DS (reference)* | 0.633 | – | – | – | – | – |
| % DS+WSS | 0.659 | 0.402 | 0.533 | 0.106 | 0.001 | 0.776 |
*Results of % DS were taken as reference values for analyses.
AUC, area under the curve; DS, diameter stenosis; IDI, integrated discrimination improvement; NRI, net reclassification index; WSS, wall shear stress.