Baseline demographic characteristics, mode of presentation and symptoms at initial evaluation in black versus white patients with HCM
| Parameter | Black patients (n=163) | White patients (n=262) | p Value |
|---|---|---|---|
| Age at diagnosis (years) | 51.5±15.9 | 50.5±17.7 | 0.712 |
| Age at first evaluation (years) | 52.4±15.9 | 52.6±17.1 | 0.883 |
| Male gender—n (%) | 107 (65.6) | 165 (66.8) | 0.807 |
| History of hypertension | 95 (58.3) | 83 (31.7) | <0.001 |
| Systolic blood pressure (mm Hg) | 130±15 | 125±17 | 0.003 |
| Diastolic blood pressure (mm Hg) | 77±11 | 74±11 | 0.017 |
| Follow-up duration (years) | 3.8±3.1 | 4.2±3.6 | 0.123 |
| Family history of HCM—n (%) | 31 (19.0) | 76 (29.0) | 0.021 |
| Mode of presentation—n (%) | |||
| Cardiovascular symptoms | 96 (58.9) | 166 (63.4) | 0.929 |
| Familial screening | 11 (6.7) | 46 (17.6) | 0.001 |
| Cardiac arrest | 5 (3.1) | 0 (0.0) | 0.008 |
| Fortuitous | 51 (31.3) | 50 (19.1) | 0.004 |
| Abnormal ECG | 44 (27.0) | 28 (10.7) | <0.001 |
| Abnormal examination | 4 (2.5) | 17 (6.5) | 0.062 |
| Pre-participation screening | 3 (1.8) | 5 (1.9) | 0.960 |
| Symptoms at initial evaluation—n (%) | 134 (82.2) | 202 (77.1) | 0.208 |
| Chest pain | 83 (50.9) | 111 (42.4) | 0.085 |
| Breathlessness | 71 (43.6) | 127 (48.5) | 0.323 |
| Palpitation | 63 (38.7) | 97 (37.0) | 0.736 |
| Pre-syncope | 24 (14.7) | 42(16.0) | 0.718 |
| Syncope | 37 (22.7) | 43 (16.4) | 0.107 |
HCM, hypertrophic cardiomyopathy.