Differences in the percentage of patients and controls with CV risk assessed and treated over time
| RA patients | RA controls | ORs (95% CI) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| 1 year before | 1 year after | 5 years after | 1 year before | 1 year after | 5 years after | 1 year before | 1 year after | 5 years after | |
| BP recorded | 130 (12) | 125 (11) | 347 (31) | 427 (10) | 385 (9) | 1188 (28) | 1.14 (0.89 to 1.46) | 1.50 (1.10 to 1.90) | 1.40 (1.15 to 1.70) |
| Hypertension* | 329 (29) | 472 (43) | 545 (49) | 1085 (26) | 1130 (26) | 1728 (40) | 1.07 (0.59 to 1.94) | 1.99 (1.20 to 3.28) | 1.28 (0.94 to 1.76) |
| AHT | 39 (3) | 107 (10) | 268 (24) | 135 (3) | 307 (7) | 808 (19) | 0.93 (0.60 to 1.47) | 1.32 (0.94 to 1.85) | 1.40 (1.12 to 1.75) |
| TC recorded | 150 (13) | 128 (11) | 390 (35) | 473 (11) | 406 (9) | 1253 (29) | 1.34 (1.05 to 1.72) | 1.15 (0.88 to 1.49) | 1.21 (0.98 to 1.48) |
| High cholesterol† | 59 (5) | 50 (4) | 148 (13) | 206 (5) | 173 (4) | 578 (13) | 1.19 (0.83 to 1.69) | 0.98 (0.67 to 1.43) | 0.83 (0.65 to 1.05) |
| LLD recorded | 18 (2) | 55 (5) | 167 (15) | 55 (1) | 203 (5) | 556 (13) | 1.33 (0.68 to 2.65) | 1.02 (0.68 to 1.55) | 1.20 (0.93 to 1.55) |
| Smoking recorded | 257 (23) | 235 (21) | 427 (38) | 736 (17) | 664 (15) | 1346 (32) | 1.57 (1.29 to 1.90) | 1.44 (1.17 to 1.77) | 1.25 (1.05 to 1.50) |
| Current smoker | 149 (13) | 127 (11) | 205 (18) | 341 (8) | 317 (7) | 591 (14) | 1.88 (1.48 to 2.38) | 1.69 (1.30 to 2.20) | 1.45 (1.17 to 1.80) |
| BMI recorded | 150 (13) | 139 (13) | 374 (34) | 436 (10) | 351 (8) | 1226 (28) | 1.52 (1.19 to 1.93) | 1.49 (1.15 to 1.92) | 1.21 (0.99 to 1.48) |
| Obesity‡ | 50 (4) | 54 (5) | 144 (13) | 163 (4) | 120 (3) | 486 (11) | 1.38 (0.94 to 2.00) | 1.64 (1.12 to 2.40) | 1.06 (0.83 to 1.34) |
| Diabetes mellitus | 88 (8) | 120 (11) | 270 (24) | 279 (7) | 323 (8) | 846 (20) | 1.30 (0.94 to 1.80) | 1.42 (1.07 to 1.89) | 1.22 (0.99 to 1.48) |
| CVD risk scores§ | 31 (3) | 28 (2) | 121 (11) | 144 (3) | 143 (3) | 479 (11) | 0.72 (0.46 to 1.14) | 0.79 (0.50 to 1.26) | 0.91 (0.70 to 1.18) |
| QRISK score data¶ | 45 (4) | 22 (2) | 191 (17) | 129 (3) | 86 (2) | 685 (16) | 1.42 (0.76 to 2.68) | 0.93 (0.84 to 4.46) | 1.22 (0.91 to 1.63) |
| IBD patients | IBD controls | ORs (95% CI) | |||||||
| 1 year before | 1 year after | 5 years after | 1 year before | 1 year after | 5 years after | 1 year before | 1 year after | 5 years after | |
| BP recorded | 248 (13) | 234 (12) | 520 (28) | 716 (10) | 620 (8) | 1662 (23) | 1.36 (1.13 to 1.64) | 1.58 (1.30 to 1.91) | 1.37 (1.16 to 1.61) |
| Hypertension | 246 (14) | 362 (19) | 430 (23) | 977 (14) | 957 (13) | 1440 (20) | 1.77 (0.96 to 3.24) | 2.07 (0.99 to 4.32) | 1.30 (0.88 to 1.92) |
| AHT | 32 (4) | 77 (7) | 213 (11) | 112 (2) | 287 (4) | 730 (10) | 1.16 (0.72 to 1.87) | 1.12 (0.78 to 1.62) | 1.19 (0.94 to 1.49) |
| TC recorded | 206 (11) | 177 (10) | 549 (29) | 672 (10) | 648 (9) | 2026 (28) | 1.27 (1.01 to 1.60) | 1.09 (0.86 to 1.39) | 1.13 (0.94 to 1.34) |
| High cholesterol | 61 (3) | 47 (3) | 154 (8) | 190 (3) | 203 (3) | 648 (9) | 1.23 (0.88 to 1.74) | 0.82 (0.56 to 1.120) | 0.79 (0.63 to 0.98) |
| LLD recorded | 16 (1) | 47 (3) | 142 (8) | 26 (0) | 175 (2) | 440 (7) | 3.21 (1.44 to 7.15) | 0.98 (0.63 to 1.54) | 1.05 (0.80 to 1.36) |
| Smoking recorded | 422 (23) | 319 (17) | 576 (31) | 1113 (15) | 903 (13) | 1920 (26) | 1.49 (1.27 to 1.79) | 1.32 (1.11 to 1.57) | 1.16 (0.99 to 1.34) |
| Current smoker | 183 (10) | 146 (8) | 255 (14) | 590 (8) | 490 (7) | 942 (13) | 1.17 (0.95 to 1.43) | 1.12 (0.89 to 1.40) | 0.98 (0.81 to 1.18) |
| BMI recorded | 332 (18) | 235 (12) | 520 (27) | 720 (10) | 573 (8) | 1606 (22) | 2.24 (1.87 to 2.68) | 1.61 (1.32 to 1.96) | 1.31 (1.12 to 1.53) |
| Obesity | 40 (2) | 41 (2) | 119 (6) | 197 (3) | 220 (3) | 571 (8) | 0.80 (0.54 to 1.18) | 0.72 (0.48 to 1.06) | 0.77 (0.60 to 0.98) |
| Diabetes mellitus | 73 (4) | 115 (6) | 255 (14) | 245 (3) | 365 (5) | 883 (12) | 1.20 (0.84 to 1.71) | 1.28 (0.97 to 1.61) | 1.14 (0.94 to 1.39) |
| CVD risk scores | 33 (2) | 32 (2) | 111 (6) | 156 (2) | 123 (2) | 430 (6) | 0.71 (0.46 to 1.10) | 0.90 (0.56 to 1.44) | 0.90 (0.72 to 1.22) |
| QRISK score data | 123 (11) | 35 (2) | 142 (17) | 514 (12) | 162 (2) | 542 (16) | 0.81 (0.41 to 1.59) | 1.47 (0.81 to 2.68) | 1.19 (0.90 to 1.56) |
Figures are frequencies and percentages, unless otherwise stated.
*Hypertension defined as systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg.
†High cholesterol defined as total cholesterol ≥5.0 mmol/L.
‡Obesity defined as BMI ≥30 kg/m2.
§Risk score recorded by practitioners.
¶QRISK scores in the year before diagnosis defined as between registration and diagnosis.
AHT, antihypertensive drugs; BMI, body mass index; BP, blood pressure; CVD, cardiovascular disease; IBD, inflammatory bowel disease; LLD, lipid-lowering drugs; RA, rheumatoid arthritis; TC, total cholesterol.