Table 2

Univariable and multivariable regression analyses of the predictors of mean transvalvular gradient

 Univariable analysisMultivariable analysis
Standardised βp ValueStandardised βp Value
Whole cohort (n=200)
Age−0.100.15−0.210.02
Men0.100.16−0.060.36
Height0.070.36
Weight−0.050.48
Body mass index−0.090.23
Body surface area−0.0090.90
√AVCd0.44<0.00010.59<0.0001
BAV0.220.0020.180.04
Hypertension−0.010.88
Dyslipidemia−0.010.84
Diabetes−0.140.046−0.080.18
History of smoking−0.110.11
Coronary artery disease−0.070.33
TAV (n=161)
Age0.150.054−0.060.36
Men0.190.020.010.82
Height0.100.23
Weight−0.030.70
Body mass index−0.070.40
Body surface area0.020.84
√AVCd0.63<0.00010.65<0.0001
Hypertension0.140.080.020.78
Dyslipidemia0.110.15
Diabetes−0.110.17
History of smoking−0.040.61
Coronary artery disease0.020.79
BAV (n=39)
Age−0.130.43−0.490.02
Men0.020.90−0.320.10
Height−0.070.66
Weight−0.020.92
Body mass index0.010.94
Body surface area−0.030.87
√AVCd0.240.140.670.005
Hypertension0.0050.98
Dyslipidemia0.0030.99
Diabetes−0.090.58
History of smoking−0.210.20
Coronary artery disease−0.110.52
TAV<72 years old (n=77)
Men0.130.25−0.040.67
Height0.060.60
Weight0.020.85
Body mass index0.030.81
Body surface area0.050.67
√AVCd0.66<0.00010.63<0.0001
Hypertension0.250.030.130.16
Dyslipidemia0.180.12
Diabetes−0.220.06−0.210.02
History of smoking−0.080.52
Coronary artery disease0.080.48
TAV≥72 years old (n=84)
Men0.250.020.080.37
Height0.150.17
Weight−0.070.51
Body mass index−0.170.13
Body surface area0.0040.97
√AVCd0.60<0.00010.58<0.0001
Hypertension0.030.76
Dyslipidemia0.040.70
Diabetes−0.0050.96
History of smoking−0.0090.94
Coronary artery disease−0.050.65
BAV<51 years old (n=18)
Men−0.180.48−0.320.36
Height−0.280.27
Weight0.050.84
Body mass index0.240.33
Body surface area−0.030.90
√AVCd−0.0050.990.210.55
Hypertension−0.050.83
Dyslipidemia−0.090.73
Diabetes
History of smoking−0.350.15
Coronary artery disease−0.140.59
BAV≥51 years old (n=21)
Men0.270.24−0.180.41
Height0.170.46
Weight−0.110.64
Body mass index−0.280.22
Body surface area−0.020.93
√AVCd0.670.0010.770.002
Hypertension0.080.74
Dyslipidemia0.090.68
Diabetes−0.150.51
History of smoking−0.090.69
Coronary artery disease
  • Significant p values are highlighted in bold.

  • AVCd, aortic valve calcification density; BAV, bicuspid aortic valve; TAV, tricuspid aortic valve.