Incidence rates (95% CIs) per 100 person-years of ischaemic stroke by CHA2DS2-VASC scores, sex and use of warfarin
| With warfarin | Without warfarin | Population overall | |||||
|---|---|---|---|---|---|---|---|
| Events | Rate | Events | Rate | p Value | Events | Rate | |
| CHA2DS2-VASc scores | |||||||
| Overall population | |||||||
| 0 | 7 | 0.4 (0.2 to 0.8) | 21 | 0.2 (0.1 to 0.3) | 0.23 | 28 | 0.2 (0.2 to 0.4) |
| 1 | 27 | 0.4 (0.3 to 0.7) | 126 | 0.7 (0.6 to 0.8) | 0.03 | 153 | 0.6 (0.5 to 0.7) |
| 2 | 87 | 0.8 (0.7 to 1.0) | 366 | 1.4 (1.3 to 1.6) | 0.00 | 453 | 1.2 (1.1 to 1.3) |
| 3 | 144 | 1.0 (0.9 to 1.2) | 869 | 2.6 (2.5 to 2.8) | 0.00 | 1013 | 2.2 (2.0 to 2.3) |
| 4 | 226 | 1.7 (1.5 to 2.0) | 1447 | 4.0 (3.8 to 4.2) | 0.00 | 1673 | 3.4 (3.2 to 3.6) |
| 5 | 233 | 3.2 (2.8 to 3.6) | 1183 | 6.2 (5.8 to 6.5) | 0.00 | 1416 | 5.3 (5.1 to 5.6) |
| 6 | 159 | 4.2 (3.6 to 4.8) | 1201 | 12.1 (11.4 to 12.8) | 0.00 | 1360 | 9.9 (9.4 to 10.4) |
| 7 | 111 | 7.1 (5.9 to 8.6) | 581 | 14.5 (13.4 to 15.7) | 0.00 | 692 | 12.4 (11.5 to 13.4) |
| 8 | 18 | 4.8 (3.0 to 7.6) | 167 | 17.6 (15.1 to 20.5) | 0.00 | 185 | 14.0 (12.1 to 16.2) |
| 9 | 3 | 7.5 (2.4 to 23.3) | 29 | 24.3 (16.9 to 35.0) | 0.03 | 32 | 20.1 (14.2 to 28.4) |
| 0–9 | 1015 | 1.7 (1.6 to 1.8) | 5990 | 3.8 (3.7 to 3.9) | 0. 00 | 7005 | 3.2 (3.2 to 3.3) |
| Men | |||||||
| 0 | 7 | 0.4 (0.2 to 0.8) | 21 | 0.2 (0.1 to 0.3) | 0.23 | 28 | 0.2 (0.2 to 0.4) |
| 1 | 25 | 0.5 (0.3 to 0.7) | 112 | 0.8 (0.6 to 0.9) | 0.01 | 137 | 0.7 (0.6 to 0.8) |
| 2 | 75 | 0.9 (0.7 to 1.1) | 306 | 1.7 (1.5 to 1.9) | 0.00 | 381 | 1.5 (1.3 to 1.6) |
| 3 | 106 | 1.3 (1.1 to 1.5) | 550 | 2.9 (2.7 to 3.2) | 0.00 | 656 | 2.4 (2.2 to 2.6) |
| 4 | 119 | 2.2 (1.8 to 2.6) | 489 | 4.3 (3.9 to 4.7) | 0.00 | 608 | 3.6 (3.3 to 3.9) |
| 5 | 122 | 4.1 (3.4 to 4.9) | 491 | 7.8 (7.1 to 8.5) | 0.00 | 613 | 6.6 (6.1 to 7.1) |
| 6 | 51 | 4.1 (3.1 to 5.4) | 312 | 11.5 (10.3 to 12.9) | 0.00 | 363 | 9.2 (8.3 to 10.1) |
| 7 | 27 | 6.1 (4.3 to 9.2) | 129 | 14.5 (12.2 to 17.3) | 0.00 | 156 | 11.9 (10.1 to 13.9) |
| 8 | 1 | 1.9 (0.3 to 13.3) | 20 | 14.5 (9.4 to 22.5) | 0.01 | 21 | 11.0 (7.2 to 16.8) |
| 0–8 | 533 | 1.6 (1.4 to 1.7) | 2430 | 2.9 (2.8 to 3.1) | 0.00 | 2963 | 2.5 (2.4 to 2.6) |
| Women | |||||||
| 1 | 2 | 0.4 (0.1 to 1.5) | 14 | 0.4 (0.2 to 0.7) | 0.97 | 16 | 0.4 (0.3 to 0.7) |
| 2 | 12 | 0.5 (0.3 to 0.9) | 60 | 0.7 (0.6 to 0.9) | 0.24 | 72 | 0.7 (0.5 to 0.8) |
| 3 | 38 | 0.7 (0.5 to 1.0) | 319 | 2.3 (2.0 to 2.5) | 0.00 | 357 | 1.8 (1.6 to 2.0) |
| 4 | 107 | 1.4 (1.1 to 1.7) | 958 | 3.9 (3.7 to 4.1) | 0.00 | 1065 | 3.3 (3.1 to 3.5) |
| 5 | 111 | 2.5 (2.1 to 3.0) | 692 | 5.4 (5.0 to 5.8) | 0.00 | 803 | 4.7 (4.4 to 5.0) |
| 6 | 108 | 4.2 (3.5 to 5.0) | 889 | 12.3 (11.5 to 13.1) | 0.00 | 997 | 10.2 (9.5 to 10.8) |
| 7 | 84 | 7.4 (6.0 to 9.2) | 452 | 14.5 (13.2 to 15.9) | 0.00 | 536 | 12.6 (11.6 to 13.7) |
| 8 | 17 | 5.3 (3.3 to 8.5) | 147 | 18.1 (15.4 to 21.3) | 0.00 | 164 | 14.5 (12.4 to 16.9) |
| 9 | 3 | 7.5 (2.4 to 23.3) | 29 | 24.3 (16.9 to 35.0) | 0.03 | 32 | 20.1 (14.2 to 28.4) |
| 1–9 | 482 | 2.0 (1.8 to 2.1) | 3560 | 4.8 (4.6 to 4.9) | 0.00 | 4042 | 4.1 (3.9 to 4.2) |