Table 1

Anatomical defects and baseline characteristics

Anatomical defect, n (%)n=20
Ventricular septal defect (VSD)5 (25.0%)
Pulmonary atresia+VSD and aortopulmonary collaterals*3 (15%)
Isolated atrial septal defect3 (15%)
Isolated patent ductus arteriosus2 (10%)
Double outlet right ventricle+aortic coarctation2 (10%)
Truncus arteriosus2 (10%)
Atrioventricular septal defect1 (5%)
Single ventricle1 (5%)
ccTGA+VSD1 (5%)
Baseline characteristics
 Age at first pregnancy, years26±6
 Simple/complex CHD, n10/10
 BMI, mean±SD19.2±2.7
NYHA functional class, n (%)
 I4 (20%)
 II13 (65%)
 III3 (15%)
 IV0 (0%)
Saturation, %87±6
Haemoglobin, g/dL17.0±1.7
Haematocrit, %49.8±6.5
Invasive pulmonary arterial pressure (S/D/M), mm Hg*101±16/43±13/62±13
  • *Pulmonary arterial hypertension was confirmed in all cases by catheterisation. Pulmonary pressures were invasively measured in 7/20 patients before pregnancy, including the three patients with segmental pulmonary hypertension. Among patients without invasive measurement of pulmonary pressures, non-invasive pulmonary pressures were available in three patients using echo-Doppler method: in one patient with atrial septal defect, systolic pulmonary pressure was estimated as 90 mm Hg, and in two patients with isolated ventricular septal defect, mean pulmonary pressure was estimated respectively as 45 and 57 mm Hg.

  • BMI, body mass index; ccTGA, congenitally corrected transposition of the great arteries; CHD, congenital heart disease; NYHA, New York Heart Association.