Baseline imaging assessment
| All (n=37) | Acute myocardial infarction group (n=21) | Chronic total occlusion group (n=7) | Control group (n=9) | p Value* | |
|---|---|---|---|---|---|
| CMR imaging | |||||
| LVEF (%) | 58±10 | 52±9 | 62±8 | 65±5 | <0.001 |
| LV mass (indexed, g/m2) | 79±20 | 85±20 | 66±17 | 75±16 | 0.07 |
| LVEDV (mL/m2) | 77±18 | 80±18 | 69±13 | 76±17 | 0.35 |
| LVESV (mL/m2) | 34±13 | 39±14 | 30±10 | 27±9 | 0.046 |
| WMI | 0.25±0.13 | 0.40±0.20 | 0.09±0.05 | 0.0±0.0 | <0.001 |
| ECV (%) | 31±5 | 34±4 | 28±3 | 28±2 | <0.001 |
| Presence of LGE | 27 (73) | 21 (100) | 6 (86) | 0 (0) | <0.001 |
| Infarct size (g/m2) | 8±8 | 12±7 | 8±8 | 0±0 | <0.001 |
| PET imaging | |||||
| SUVmean (kBq/mL) | |||||
| SVC | 2.73±0.51 | 2.85±0.51 | 2.57±0.39 | 2.58±0.57 | 0.27 |
| Total LV uptake | 2.24±0.51 | 2.33±0.48 | 1.96±0.53 | 1.77±0.27 | <0.001 |
| Myocardial infarct uptake | 3.23±1.03 | 3.72±0.63 | 1.76±0.26 | – | <0.001 |
| Remote myocardial uptake | 2.21±0.60 | 2.41±0.57 | 1.62±0.14 | – | 0.001 |
| TBRmean | |||||
| Total LV uptake | 0.77±0.16 | 0.82±0.18 | 0.71±0.06 | 0.70±0.03 | 0.08 |
| Myocardial infarct uptake | 1.05±0.37 | 1.34±0.22 | 0.70±0.14 | – | <0.001 |
| Remote myocardial uptake | 0.80±0.18 | 0.85±0.17 | 0.64±0.12 | – | 0.009 |
| SUVmax (kBq/mL) | |||||
| Total LV uptake | 2.71±0.58 | 2.86±0.56 | 2.24±0.40 | 2.07±0.31 | <0.001 |
| Myocardial infarct uptake | 3.53±1.00 | 3.98±0.68 | 2.18±0.35 | – | <0.001 |
| Remote myocardial uptake | 2.59±0.64 | 2.75±0.65 | 2.18±0.35 | – | 0.02 |
| TBRmax | |||||
| Total LV uptake | 0.98±0.19 | 1.02±0.19 | 0.89±0.20 | 0.81±0.09 | 0.01 |
| Myocardial infarct uptake | 1.28±0.34 | 1.42±0.25 | 0.86±0.16 | – | <0.001 |
| Remote myocardial uptake | 0.94±0.19 | 0.97±0.20 | 0.84±0.13 | – | 0.11 |
| SUVC (kBq/mL) | |||||
| Total LV uptake | −0.55±0.57 | −0.52±0.55 | −0.61±0.67 | 0.81±0.42 | 0.85 |
| Myocardial infarct uptake | 0.75±0.91 | 1.13±0.67 | −0.40±0.46 | – | <0.001 |
| Remote myocardial uptake | −0.19±0.52 | −0.11±0.54 | −0.45±0.37 | – | 0.12 |
*Analysis of variance, Student’s t-test (continuous data) or χ2 test (categorical data).
Mean±SD or number (percentage).
CMR, cardiac magnetic resonance; ECV, extracellular volume; LGE, late gadolinium enhancement; LV, left ventricular; LVEDV, LV end diastolic volume; LVEF, LV ejection fraction; LVESV, LV end systolic volume; PET, positron emission tomography; SUV, standardised uptake value; SUVC, corrected SUV; SUVmax, maximum SUV; SVC, superior vena cava; TBR, tissue-to-background ratio; WMI, wall motion index.