Regression analysis evaluating TTNtv and hypertension as predictors of LVEF
Unadjusted analysis | Adjusted analysis* | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Variable | Estimate (change in LVEF,%) | 95% confidence intervals | P value | Estimate (change in LVEF,%) | 95% confidence intervals | P value | ||||
Baseline: No TTNtv or hypertension | 0 | - | - | 0 | - | - | ||||
TTNtv, no hypertension | −1.6 | −4.7 to 1.5 | 0.31 | −2.4 | −5.4 to 3.6 | 0.11 | ||||
Hypertension, no TTNtv | −0.4 | −2.5 to 1.7 | 0.71 | 1.7 | −0.3 to 3.6 | 0.10 | ||||
TTNtv and hypertension | −1.6 | −9.4 to 6.2 | 0.70 | 1.4 | −5.8 to 8.7 | 0.70 | ||||
TTNtv*hypertension interaction§ | 0.5 | −8.0 to 8.9 | 0.92 | 2.2 | −5.7 to 10.1 | 0.58 |
Table shows unadjusted univariable and adjusted multivariable analyses of the effect of TTNtv and hypertension on baseline left ventricular ejection fraction.
*Adjusted for gender, a family history of DCM, a history of atrial fibrillation and the presence of mid wall fibrosis (late gadolinium enhancement on CMR) and NYHA class.
§ i.e. the effect of TTNtv and hypertension compared to either TTNtv alone or hypertension alone.