Univariable and multivariable predictors of all-cause mortality
| Univariable | Multivariable | ||||
|---|---|---|---|---|---|
| HR | p Value | HR | 95% CI | p Value | |
| Patient characteristics | |||||
| Male gender | 0.68 | 0.20 | |||
| Age at inclusion (per year older) | 1.08 | <0.001 | 1.07 | 1.04 to 1.09 | <0.001 |
| TOF with pulmonary atresia | 1.02 | 0.82 | |||
| Surgical and clinical characteristics | |||||
| Previous shunt procedure | 2.44 | <0.001 | 2.20 | 1.22 to 3.97 | 0.008 |
| Previous supraventricular tachycardia | 8.89 | <0.001 | |||
| Previous ventricular arrhythmia | 2.86 | 0.05 | |||
| Pulmonary valve replacement | 1.10 | 0.90 | |||
| Pacemaker implantation | 6.87 | <0.001 | 3.12 | 1.48 to 6.57 | 0.003 |
| ICD implantation | 5.93 | 0.001 | |||
| ECG | |||||
| Heart rate (beats per minute) | 1.03 | 0.01 | |||
| Rhythm | |||||
| Sinus rhythm | 0.21 | <0.001 | |||
| Atrial rhythm | 2.34 | 0.07 | |||
| Atrial fibrillation | 8.87 | <0.001 | |||
| Other | 3.89 | 0.002 | |||
| QRS morphology | |||||
| RBBB | 0.67 | 0.19 | |||
| Other | 5.50 | <0.001 | |||
| QRS duration (ms) | 1.02 | <0.001 | |||
| QRS >180 ms | 5.83 | <0.001 | |||
| JTc duration (ms) | 1.01 | 0.13 | |||
| JTc >320 ms | 1.47 | 0.08 | |||
| At least one PVC | 3.74 | <0.001 | |||
| Extent of fQRS (per class (0–2)) | 3.20 | <0.001 | 2.24 | 1.48 to 3.40 | <0.001 |
Univariable and multivariable Cox hazards regression analyses for the primary endpoint all-cause mortality. The predictive value of variables is expressed as HR with 95% CI and p values.
fQRS, fragmented QRS complexes; ICD, implantable cardioverter defibrillator; JTc, corrected JT interval; PVC, premature ventricular complex; RBBB, right bundle branch block; TOF, tetralogy of Fallot.