Table 3

Univariable analysis for predictors of atrial fibrillation in hypertrophic cardiomyopathy

Univariable analysis
Predictor	HR	CI	p Value
Female	1.27	1.10 to 1.47	<0.001
Age (10 years increment)	1.35	1.29 to 1.41	<0.001
NYHA II	1.75	1.49 to 2.05	<0.001
NYHA III,IV	2.96	2.37 to 3.69	<0.001
LA (5 mm increment)	1.6	1.53 to 1.68	<0.001
MWT (mm)	1.02	1.01 to 1.03	<0.001
FS (%)	0.87	0.38 to 2.01	0.75
LVOT max (mm Hg)	1.01	1.00 to 1.01	<0.001
LVEDD (mm)	1.02	1.01 to 1.03	<0.001
LVESD (mm)	1.01	1.00 to 1.03	0.02
Hypertension	1.72	1.48 to 2.01	<0.001
Diabetes	1.52	1.16 to 1.99	<0.001
Vascular disease	2.4	1.61 to 3.58	<0.001
Analyses with non-linear terms
MWT (mm)	1.21	1.11 to 1.31	<0.001
MWT²	1	0.996 to 1.00	<0.001
LA5	3.11	1.98 to 4.87	<0.001
LA5²	0.97	0.94 to 0.99	<0.001

MWT and MWT² in the last two rows of the table adjust for MWT and its square term and similarly for LA5.
Age 10, HR for 10-year increments; FS, fractional shortening; LA, left atrial; LA5, HR for LA size for 5 mm increments; LVEDD, left ventricular end-diastolic dimension; LVESD, left ventricular end-systolic dimension; LVOT max, maximum LV outflow gradient; MWT, maximal wall thickness; NYHA, New York Heart Association Functional Classification.