Table 1

Demographic data and patient characteristics

No PAH
group A
PAH
group B
Postcapillary PH
Group C
PAPmean ≥25 mm Hg, PAWP >15 mm Hg
Group A1
PAPmean <21 mm Hg
Group A2
PAPmean 21–24 mm Hg
Group B1
PAPmean 25–36 mm Hg
Group B2
PAPmean ≥37 mm Hg
Patient characteristics
 N1154810
98172325
 M/F19/965/432/8
17/812/153/202/23
 Age (years)55±1367±966±9
54±1259±1465±969±8
 Height (cm)167±8164±9165±5
168±7164±8164±10164±9
 Weight (kg)71±1371±1569±9
70±1474±1274±1468±20
 Disease duration (months)82±9187±86150±131
88±9553±50100±9776±75
Pulmonary function testing
 TLC (% predicted)96.9±18.988.6±25.795.0±18.9
98.4±18.488.4±20.085.2±29.891.8±21.2
 DLCO (% predicted)64.6±19.342.6±11.662.6±23.7
64.6±18.864.5±22.642.8±11.942.4±11.7
Echocardiography
 LV ejection fraction (%)67.3±9.964.2±7.270.0±8.7
68.0±10.263.2±6.964.2±6.764.2±7.6
 RV diameter (mm)30.0±5.633.4±7.629.4±3.7
29.5±5.332.7±6.731.3±7.135.1±7.7
 TRPG (mm Hg)23.7±11.260.2±24.336.7±13.8
22.7±10.630.1±13.342.2±16.176.0±18.7
Haemodynamic measurements by RHC
 PAPsyst (mm Hg)26.0±5.763.4±21.642.7±10.5
24.7±4.834.1±3.844.7±7.980.6±14.6
 PAPmean (mm Hg)16.3±3.738.2±11.529.3±4.1
15.3±3.021.9±1.328.2±2.947.4±8.1
 PAPdiast (mm Hg)9.8±3.023.0±8.3
9.2±2.613.1±2.617.7±4.428.0±7.818.2±4.3
 PAWP (mm Hg)7.7±3.210.3±3.419.3±2.4
7.2±2.710.7±4.210.5±3.610.2±3.4
 TPG (mm Hg)8.6±2.827.9±12.210.0±3.2
8.1±2.411.2±3.917.7±4.537.3±9.1
 DPG (mm Hg)2.2±2.912.7±9.1−1.1±4.7
2.1±2.82.4±4.07.2±5.218.0±8.9
 CI (L/min/m2)3.0±0.62.4±0.63.1±0.6
3.0±0.72.9±0.62.6±0.62.2±0.6
 PVR (WU)1.7±0.77.8±6.41.9±0.9
1.6±0.62.3±1.24.1±1.711.4±7.2
  • Values are presented as group mean±SD.

  • CI, cardiac index; DLCO, diffusing capacity for carbon monoxide; DPG, diastolic pressure gradient; PAH, pulmonary arterial hypertension; PAP, pulmonary arterial pressure; PAWP, pulmonary arterial wedge pressure; PH, pulmonary hypertension; PVR, pulmonary vascular resistance; RHC, right heart catheterisation; RV, right ventricular; TLC, total lung capacity; TPG, transpulmonary pressure gradient; TRPG, tricuspid regurgitation pressure gradient; WU, Wood units.