Table 2

Associations of patient characteristics with major infection and univariate logistic regression models for major infection

Patient characteristics	Number of cases	Number of infections	Infection rate	p Value	OR*	95% CI	p Value
Time period				<0.001
Pre-IQIC	334	110	29.9%		1	–	–
Transition	102	32	31.4%		1.1	0.7 to 1.7	0.78
Post-IQIC	285	3	1.1%		0.03	0.01 to 0.08	<0.001
Age category				<0.001
≤30 days	43	15	34.9%		3.1	1.6 to 6.2	<0.001
31 days to <1 year	197	53	26.9%		2.1	1.4 to 3.2	<0.001
1 to <18 years	409	60	14.7%		1	–	–
≥18 years	71	6	8.5%		0.5	0.2 to 1.3	0.17
Malnutrition				0.03
Normal/overweight	384	58	15.1%		1	–	–
Malnourished	288	65	22.6%		1.6†	1.1 to 2.4	0.01
Emaciated	38	9	23.7%
Premature				0.23
Yes	11	0	0.0%
No	710	135	19.0%
Major chromosomal abnormality				0.10
Yes	24	8	33.3%		2.2	0.9 to 5.3	0.07
No	696	127	18.3%
Major non-cardiac structural anomaly				1
Yes	7	1	14.3%
No	714	134	18.8%
Major medical illness				1
Yes	21	4	19.1%
No	700	131	18.7%
Oxygen saturation <85%				0.001
Yes	164	45	27.4%		2.1	1.4 to 3.2	<0.001
No	527	81	15.4%
RACHS-1 risk category				0.02
1	122	15	12.3%		1	–	–
2	439	78	17.8%		1.5	0.8 to 2.6	0.20
3	149	39	26.2%		2.4‡	1.23 to 4.5‡	0.008‡
4	9	2	22.2%

*Univariate logistic regression models on variables with p≤0.10.
†Malnourished and emaciated cases are combined for analysis.
‡Risk categories 3 and 4 are combined for analysis.
IQIC, International Quality Improvement Collaborative; RACHS, Risk Adjustment for Congenital Heart Surgery.