Multivariable Cox proportional hazards analysis for predicting cardiac death and composite endpoint (200 imputations)
| Variables* | Cardiac death | Composite endpoint | ||
| HR (95% CI)† | p Value | HR (95% CI)† | p Value | |
| Age (years) | 1.064 (1.037 to 1.091) | <0.001 | 1.022 (1.008 to 1.057) | 0.003 |
| NYHA functional class III/IV | 3.958 (1.526 to 10.268) | 0.003 | 1.169 (0.762 to 1.793) | 0.475 |
| Moderate or severe TR | 1.914 (1.205 to 3.036) | 0.004 | 1.558 (1.162 to 2.968) | 0.007 |
| Cn (mL/mm Hg) | 0.698 (0.488 to 0.864) | 0.008 | 0.802 (0.676 to 0.952) | 0.011 |
| Postprocedural data | ||||
| Mean gradient (mm Hg) | 1.084 (0.960 to 1.223) | 0.192 | 1.175 (1.101 to 1.253) | <0.001 |
| Moderate MR | 1.395 (0.644 to 3.022) | 0.398 | 1.860 (1.085 to 2.905) | 0.008 |
| Severe MR | 2.581 (0.559 to 11.916) | 0.224 | 6.509 (3.219 to 13.161) | <0.001 |
*Shrinkage factor: 0.9216 (cardiac death) and 0.9441 (composite endpoint).
†Shrinkage HR.
Cn, net atrioventricular compliance; MR, mitral regurgitation; NYHA, New York Heart Association; TR, tricuspid regurgitation.