Risk prediction model for 5-year cardiac mortality using a model without Cn and a model with Cn
| Multivariable predictors of late cardiac death | |||
| Variables | HR | 95% CI | p Value |
| Model without Cn | |||
| Age (years) | 1.103 | 1.066 to 1.141 | <0.001 |
| NYHA functional class III/IV | 5.285 | 2.019 to 13.836 | 0.001 |
| Moderate or severe TR | 1.976 | 1.272 to 3.069 | 0.002 |
| Model with Cn* | |||
| Age (years) | 1.102 | 1.065 to 1.141 | <0.001 |
| NYHA functional class III/IV | 5.374 | 2.055 to 14.053 | 0.001 |
| Moderate or severe TR | 2.079 | 1.305 to 3.314 | 0.002 |
| Cn (mL/mm Hg) | 0.672 | 0.504 to 0.896 | 0.007 |
*NRI of including Cn in the model: 0.568; 95% CI 0.186 to 0.849; p=0.002.
Cn, net atrioventricular compliance; NRI, net reclassification improvement; NYHA, New York Heart Association; TR, tricuspid regurgitation.