Table 2

Quality of evidence

Number of studiesQuality assessmentEffectQuality
Study designRisk of biasInconsistencyIndirectnessImprecisionOther considerationsRate
(95% CI)
Structural valve deterioration (follow-up: median 3.6 years; assessed with: Incidence per 10 000 patient years)
13ObservationalNot seriousSerious*Not seriousNot seriousNoneEvent rate
28.08 (2.46 to 73.44) per 10 000 person year(s)
⨁⨁⨁◯
MODERATE
  • *High heterogeneity across studies.