Table 3

Baseline NYHA class and echocardiographic features in the studies included in the meta-analysis

StudyNYHA 3–4 (%)MR grade 3–4 (%)LVEF (%)LVEDV, mLLVEDD, mm
Braun et al. 201414 9881839635581931396456
Chan et al. 201216 N/AN/A10010032462281566457
EVEREST II RCT65451001004864N/AN/AN/AN/A
EVEREST II HRR87848095N/AN/A170137N/AN/A
EVEREST II REALISM8684789142601621245851
Pilot European sentinel registry8877991003759172119N/AN/A
Rudolph et al. 201319 969510010037572221486860
 Pooled population8777899539581781316154
p Value<0.001<0.001<0.001<0.001<0.001
  • DMR, degenerative mitral regurgitation; EVEREST II, Endovascular Valve Edge-to-Edge Repair Study II; FMR, functional mitral regurgitation; LVEDD, left ventricular end-diastolic diameter; LVEDV, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; MR, mitral regurgitation; NYHA, New York Heart Association; RCT, randomised controlled trial.