Table 1

99th centile=the upper reference limit as determined in a healthy reference range population

99th centile
(Diagnostic threshold)
10% coefficient of variation*Limit of detection
Roche Elecsys high-sensitivity cardiac troponin T7 14 ng/L13 ng/L5 ng/L
Abbott ARCHITECTSTAT high-sensitivity cardiac troponin I8 16 ng/L (females)
34 ng/L (males)
26 ng/L (single threshold)
4.7 ng/L2 ng/L
  • Limit of detection, the lowest concentration which can be reliably distinguished from a sample with no troponin present.

  • *Lowest concentration where coefficient of variation is <10% (measure of dispersion of replicate sample results around the mean (SD/mean)).