Baseline characteristics
| Control (n=54) | Hypothermia (n=47) | |
| Age, years (SD) | 55 (±12) | 58 (±10) |
| Female gender, n (%) | 10 (19) | 10 (21) |
| Hypertension, n (%) | 25 (46) | 13 (28) |
| Diabetes, n (%) | 10 (19) | 5 (11) |
| Dyslipidaemia, n (%) | 17 (32) | 10 (21) |
| Current smoker, n (%) | 30 (56) | 26 (55) |
| Familial history of CAD, n (%) | 12 (22) | 12 (25) |
| Obesity, n (%) | 19 (35) | 10 (21) |
| Weight, kg (SD) | 89 (±18) | 82 (±20) |
| Body mass index (kg/m2), mean (SD) | 29.3 (±4.9) | 27.1 (±5.5) |
| Previous medication | ||
| Acetylsalicylic acid, n (%) | 6 (11) | 1 (2) |
| Beta blocker, n (%) | 7 (13) | 4 (9) |
| ACE-I/ARB, n (%) | 11 (20) | 8 (17) |
| Statin, n (%) | 12 (22) | 3 (6) |
| Initial sinus rhythm, n (%) | 49 (90) | 44 (94) |
| Anterior wall infarction, n (%) | 25 (46) | 27 (57) |
| Emergency therapy | ||
| Acetylsalicylic acid, n (%) | 54 (100) | 47 (100) |
| Heparin, n (%) | 54 (100) | 47 (100) |
| Prasugrel/ticagrelor | 54 (100) | 47 (100) |
| Nitroglycerin, n (%) | 12 (22) | 9 (19) |
| Beta blocker, n (%) | 3 (6) | 0 (0) |
| Infarct-related artery | ||
| LAD*, n (%) | 24 (45) | 28 (60) |
| Circumflex artery, n (%) | 4 (7) | 3 (6) |
| Right coronary artery, n (%) | 25 (46) | 16 (34) |
| Unknown, n (%) | 1 (2) | 0 (0) |
| Multivessel disease, n (%) | 31 (59) | 22 (47) |
| Initial TIMI† 0/1, n (%) | 43 (81) | 34 (72) |
No statistically significant difference between baseline variables (except for previous use of statins; p=0.03).
*Left anterior descending artery
†Thrombolysis in myocardial infarction grade flow.
ACE-I, ACE inhibitor; ARB, angiotensin receptor blocker; CAD, coronary artery disease; LAD, left anterior descending artery.