Table 4

Risk of adverse outcomes considering marital status in specific groups of participants

OutcomeMarital status and subgroupsStudiesNo. of participants (not applicable, (NA) for studies with no crude result available)Odds ratio (95% CI)Overall effect, P valueHeterogeneity, I%Subgroup differences between men only and women only (P value, I2)
Mortality post strokeUnmarried vs married
  All329 4191.08 (0.88 to 1.32)0.4743
  Women only131560.95 (0.77 to 1.17)0.62
  Men and women226 2631.24 (0.83 to 1.84)0.2924
Mortality post MIUnmarried vs married
  All11>21456 (3 NA)1.42 (1.14 to 1.76)0.00283
  Men only2>2453 (1 NA)1.76 (1.24 to 2.49)0.001800.56, 0%
  Women only2>374 (1 NA)1.38 (0.67 to 2.86)0.3861
  Men and women9>18629 (2 NA)1.35 (1.00 to 1.83)0.0584
Divorced vs married
  All3>4158 (1 NA)1.36 (0.92 to 2.01)0.1385
  Men only125251.91 (1.50 to 2.43)<0.0010.95, 0%
  Women only14471.87 (1.04 to 3.36)0.04
  Men and women2>1186 (1 NA)1.08 (0.95 to 1.22)0.230
Widowed vs married
  All4>9171 (1 NA)1.68 (1.30 to 2.17)<0.00185
  Men only121361.49 (0.77 to 2.89)0.240.31, 2.3%
  Women only13682.74 (1.03 to 7.28)0.04
  Men and women3>6667 (1 NA)1.65 (1.24 to 2.20)<0.00192
MI post MIUnmarried vs married
  All219640.72 (0.14 to 3.60)0.6977
  Women only12220.29 (0.08 to 1.08)0.07
  Men and women117421.51 (0.68 to 3.37)0.31
MACE post MIUnmarried vs married
  Men and women117421.31 (0.79 to 2.17)0.29
Major bleeding post MIUnmarried vs married
  Men and women117422.11 (0.55 to 8.10)0.28
CVD post MIUnmarried vs married
  Men and women118131.07 (0.41 to 2.81)0.89
  • CVD, cardiovascular disease; MACE, major adverse cardiac events; MI, myocardial infarction.