	HR (95% CI)	P values	HR (95% CI)	P values
Outcome: composite endpoint
LVEF	0.94 (0.93 to 0.95)	<0.001	0.96 (0.93 to 0.99)	0.028
e′ septal	0.85 (0.78 to 0.92)	<0.001	0.68 (0.48 to 0.97)	0.034
E/e′ septal	1.04 (1.02 to 1.05)	<0.001	1.09 (1.02 to 1.16)	0.012
EDP/LVEDVI ratio×10	0.72 (0.59 to 0.88)	0.001	1.39 (1.00 to 1.92)	0.047
EDP/LAVI ratio×10	0.80 (0.69 to 0.93)	0.004	1.62 (1.16 to 1.23)	0.004
Global longitudinal LV strain, %	1.19 (1.13 to 1.25)	<0.001	1.15 (0.98 to 1.35)	0.09

The composite endpoint was defined as the composite outcome of left ventricular assistant device implantation, heart transplantation or all-cause mortality.
CPET, cardiopulmonary exercise testing; CTHF, cancer therapy-induced heart failure; EDP, end-diastolic pressure; LAVI, left atrial volume index; LV, left ventricular; LVEF, left ventricular ejection fraction; LVEDVI, left ventricular end-diastolic volume index; NCTHF, non-cancer therapy-induced heart failure.