Table 2

Diagnostic characteristics of quantitative measures of severe aortic stenosis relative to documented severe aortic stenosis

Echocardiographic measurementsSensitivitySpecificityPositive predictive valueNegative predictive valueAccuracy
Single elements,%
 Peak velocity>4.0 m/s69.999.881.999.599.3
 Mean gradient>40 mm Hg62.399.989.199.499.3
 Aortic valve area≤1.0 cm2 94.197.637.599.997.5
 Indexed aortic valve area≤0.6 cm2/m2 97.295.123.3100.095.1
 Dimensionless Index (VTI)≤0.2579.799.159.299.798.8
 Dimensionless Index (peak velocity)≤0.2580.599.259.899.798.9
Combined elements, %
 Peak velocity or mean gradient71.999.781.299.699.3
 Peak velocity, mean gradient or valve area98.497.537.510097.5
 Peak velocity, mean gradient or indexed valve area98.995.023.510095.1
 Peak velocity, mean gradient or dimensionless index (VTI)93.999.058.499.998.9
 Peak velocity, mean gradient or dimensionless index (peak velocity)91.999.058.799.998.9
  • VTI, velocity time integral.