Table 4

Outcomes of pericardial diseases in African-based populations

First authorYear of publicationPeriod of recruitmentCountryStudy designData collectionSettingAreaDisease-specific populationTreatment receivedSample sizeMale %Mean ageAge range% of HIVDiagnostic methodDuration of follow-up (in months)Number of deceasedMortality rate (%)
Mayosi3 20082004Cameroon, Nigeria and South AfricaCohortProspectiveHospital basedUrbanPresumed tuberculous pericarditisAnti-TB treatment, steroids and pericardiocentesis.174573314–8755.2Echocardiography, ECG, bacteriology and biochemistry.064827.6
Mutyaba26 20141990–2012South AfricaCohortRetrospectiveHospital basedUrbanConstrictive pericarditisPericardiectomy.12165.341.314–7411.6Echocardiography, bacteriology and histology.011714
Strang37 2004South AfricaRCTProspectiveHospital basedNRtuberculous pericarditisAnti-TB treatment, steroids, pericardiocentesis and pericardiostomy.38343.8495–78NREchocardiography.1209625
Mynors24 19731967–1971ZimbabweCross-sectionalRetrospectiveHospital basedNRPericarditis (86% tuberculous or acute purulent)Depending on the aetiology: anti-TB treatment and pericardiectomy.57NRNRNRNRRadiology, surgery and postmortem.NR1526.3
Syed34 2013South AfricaCohortProspectiveHospital basedUrbanTuberculous pericarditis8166.736.128–5870.4Echocardiography, ECG and bacteriology.061418
Pio13 20162011–2014TogoCross-sectionalProspectiveHospital basedUrbanPericardial effusionsVariable: anti-TB treatment, pericardiocentesis and pericardiostomy.384242.516–7347Echocardiography, ECG and bacteriology.NR718
Maher36 19971993MalawiCohortProspectiveHospital basedUrbanTuberculous pericarditisAnti-TB treatment, steroids and pericardiocentesis.42NR2918–5484Echocardiography, chest X-ray, ECG and bacteriology.121023.8
Reuter51 20051995–2001South AfricaCross-sectionalRetrospectiveHospital basedUrbanTuberculous pericardial effusionAnti-TB treatment and pericardial surgery.16256.73813–8536.1Echocardiography, bacteriology and cytology.122817
Reuter51 20051995–2001South AfricaCohortRetrospectiveHospital basedUrbanPericardial malignancySurgical drainage.2256.73813–85NREchocardiography, bacteriology and cytology.122090
Reuter51 20051995–2001South AfricaCohortRetrospectiveHospital basedUrbanLarge pericardial effusionsDepending on aetiology: anti-TB treatment and pericardial surgery.23356.73813–85Echocardiography, bacteriology and cytology.127030
Sidibe16 20072005–2006MaliCross-sectionalRetrospectiveHospital basedUrbanPericardial disease in HIV patientsNR4963.340.5NR100Echocardiography, chest X-ray, ECG and bacteriology.NR1836.7
Yangni-Angate38 20161977–2012Ivory CoastCross-sectionalRetrospectiveHospital basedUrbanChronic constrictive pericarditisPericardiectomy.1206028.88–51NRChest X-ray, bacteriology and histology.NA1512.5
  • NR, not reported.