Table 2

HRs for all-cause death according to the severity and extent of obstructive CAD (n=22 828)

	Unadjusted model			Risk factor-adjusted model
	HR	95% CI	P values	HR	95% CI	P values
CCTA models
Severity of obstructive CAD
No CAD	1.00			1.00
Non-obstructive CAD	2.53	1.85 to 3.45	<0.001	1.38	0.99 to 1.91	0.056
Moderate-to-severe CAD	5.66	4.20 to 7.63	<0.001	2.34	1.69 to 3.24	<0.001
Any CTO	8.72	4.59 to 16.59	<0.001	2.65	1.32 to 5.28	0.006
Any proximal CTO	11.62	5.95 to 22.70	<0.001	3.73	1.81 to 7.66	<0.001
Extent of obstructive CAD (no. of involved vessels with ≥50% stenosis)
No CAD	1.00			1.00
Non-obstructive CAD	2.53	1.85 to 3.45	<0.001	1.40	1.01 to 1.94	0.046
One-vessel disease	3.88	2.71 to 5.54	<0.001	1.85	1.27 to 2.68	0.001
Any CTO	8.72	4.59 to 16.60	<0.001	2.71	1.36 to 5.42	0.005
Multivessel or left main disease	8.15	5.88 to 11.28	<0.001	2.97	2.08 to 4.25	<0.001
Any proximal CTO	11.62	5.95 to 22.70	<0.001	3.82	1.86 to 7.86	<0.001

Risk adjustment was performed based on differences in age, gender, cardiovascular risk factors and symptoms.
CAD, coronary artery disease; CCTA, coronary CT angiography; CTO, chronic total occlusion.