Abstract 15 Table 1

CMR and echo variables, correlations and outcomes in patients undergoing lung transplant assessment

	All patients (n=84)		Alive (n=70)		Dead (n=14)		Alive vs dead p value	HR	CI	p value

	Mean/median	SEM/IQR	Mean/median	SEM/IQR	Mean/median	SEM/IQR

Demographics
Age (years)	53	16	53	15	50	18	0,26
Gender (M)	46		37		9		0,43
BSA	1,78	0,02	1,78	0,03	1,79	0,05	0,84
Ethnicity							overall 0.90
White	72		60		12
African	2		2		0
Afro-Caribbean	6		5		1
Asian	4		3		1
Diagnosis
Underlying lung disease							overall 0.46
ILD	28		23		5
Emphysema	32		27		5
Cystic Fibrosis	15		14		1
Bronchiectasis	5		3		2
Other	3		2		1
Pulmonary hypertension (echo diagnosis, n =51 )	51		41		10		0,58
Clinical classification of patients with PH (n =51 )							overall 0.64
Group 1	3		3		0
Group 3	40		32		8
Group 5	8		6		2
Transplanted	22		15		7		0,03	2,06	0.68–6.22	0,20
MRI and Echo indices
mPAP	27	11	26	10	33	23	0,04	1,05	1.01–1.09	<0.005
CMR LVEDVI	58	23	59	24	57	19	0,93
CMR LVESVI	22	13	21	13	25	13	0,30
CMR LV StVI	38	1,54	37	1,43	39	6,04	0,63
CMR LVEF	62	1,07	63	1,14	58	2,77	0,06
CMR RVEDVI	72	32	70	28	83	62	0,01	1,03	1.01–1.04	<0.005
CMR RVESVI	41	2,62	37	2,06	64	10,14	0,02	1,03	1.01–1.04	<0.005
CMR RV StVI	37	14	37	13	35	11	0,49
CMR RVEF	51	18	53	15	38	17	,001	0,94	0.90–0.97	<0.005
CMR 4ch RAArea	16	7	16	6	20	6	0,11
LGE	14		9		5		0,04	2,45	0.79–7.61	0,12
Non-insertion point LGE	7		5		2		0,38
RV-PA coupling SV/ESV	1,03	0,72	1,12	0,67	0,57	0,48	,001	0,12	0.027–0.52	<0.005
Global FD	1,26	,004	1,26	,004	1,26	,012	0,49
Maximal Basal FD	1,33	,007	1,32	,008	1,33	,017	0,35
Mean Basal FD	1,26	,006	1,25	,007	1,28	,014	0,06
Maximal Apical FD	1,30	,007	1,30	,008	1,30	,016	0,74
Mean Apical FD	1,25	,007	1,25	,007	1,25	,016	0,80
Correlations
	RV EDVI	RV ESVI	RV SVI	RV EF	RA area	mPAP
SV/ESV
r value	−0,407	−0,712	0250	0847	−0,231	−0,301
p value	<0.001	<0.001	,022	<0.001	,042	,014
Global FD
r value	,319	,303	,130	-,203	,280	,290
p value	<0.005	,005	,238	,064	,013	,018
Maximal Basal FD
r value	,389	,350	,226	-,196	,296	,267
p value	<0.001	<0.005	,039	,073	,008	,030
Mean Basal FD
r value	,401	,373	,179	-,215	,350	,297
p value	<0.001	<0.001	,102	,050	<0.005	,016

BSA: body surface area; ILD: Interstitial lung disease; LVEDVi or RVEDVi: indexed left ventricular or right ventricular end-diastolic volume; LVESVi or RVESVi: indexed LV or RV end systolic volume; LV StVI or RV StVI: indexed LV or RV stroke volume; LVEF or RVEF: LV or RV ejection fraction; LGE: late gadolinium enhancement; FD: fractal dimension; HR: hazard ratio; CI: confidence interval, SEM/IQR: standard error of mean/interquartile range)