Table 1

Baseline characteristics of included patients

Total
(n=716)
ACS present
(n=105)
ACS absent
(n=611)
Age in years, mean (SD)57.6 (15.6)66.1 (14.6)56.2 (15.3)
Men (%)445 (62.2)78 (74.3)367 (60.1)
Previous myocardial infarction (%)169 (23.6)35 (33.3)134 (21.9)
Previous percutaneous coronary intervention (%)138 (19.3)25 (23.8)113 (18.5)
Previous coronary artery bypass graft (%)51 (7.1)12 (11.4)39 (6.4)
Hypertension (%)332 (46.4)59 (56.2)273 (44.7)
Hyperlipidaemia (%)256 (35.8)48 (45.7)208 (34.0)
Type 1 diabetes mellitus (%)14 (2.0)4 (3.8)10 (1.6)
Type 2 diabetes mellitus (%)123 (17.2)31 (29.5)92 (15.1)
Current smoking (%)139 (19.4)28 (26.7)111 (18.2)
Time from symptom onset to arrival in the ED (hours)
 0–3 354 (49.4)54 (51.4)300 (49.1)
 3–6 153 (21.4)25 (23.8)128 (20.9)
 6–9 88 (12.3)14 (13.3)74 (12.1)
 >9 73 (10.2)9 (8.6)64 (10.5)
Components of the (T-)MACS rule
 Acute ECG ischaemia (%)64 (8.9)29 (27.6)35 (5.7)
 Worsening angina (%)124 (17.3)33 (31.4)91 (14.9)
 Pain associated with vomiting (%)38 (5.3)6 (5.7)32 (5.2)
 Sweating observed (%)39 (5.4)7 (6.7)32 (5.2)
 Systolic blood Pressure<100 mm Hg (%)23 (3.2)3 (2.9)20 (3.3)
 Pain radiating to right arm or shoulder (%)63 (8.8)15 (14.3)48 (7.9)
 POC cTnI (i-Stat)≥10 ng/L (%)263 (36.7)90 (85.7)173 (28.3)
  • ACS, acute coronary syndrome; cTn, cardiac troponin; ED, emergency department; POC, point of care; T-MACS, Troponin-only Manchester Acute Coronary Syndromes.