Table 3

Clinical and echocardiographic data of studies without valvular outflow obstruction according to AVA > or ≤ 1.5 cm2

AVA >1.5 cm2 AVA ≤1.5 cm2 P value
Patients, n11 980 710
Studies, n13 774 856
Aortic valve type, n (%)<0.001
 Normal7932 (58)256 (30)
 Sclerosis5842 (42)600 (70)
Age, years65±1976±17<0.001
Sex male, n (%)6422 (54)188 (27)<0.001
Body surface area, m2 1.79±0.211.63±0.18<0.001
Peak aortic jet velocity, cm/s139±32169±34<0.001
Stroke volume (mL)71±2141±11<0.001
Aortic time–velocity integral, cm29±734±9<0.001
LVOT diameter, cm2.1±0.21.9±0.2<0.001
LVOT time–velocity integral, cm21±518±5<0.001
LV end diastolic volume, mL114±50126±570.02
LV end systolic volume, mL59±4176±51<0.001
LV ejection fraction, %58±1054±12<0.001
LV mass index, g/m2 85±2791±290.02
Relative wall thickness0.4±0.10.5±0.20.18
Mitral regurgitation, n (%)<0.001
 0–I8715 (63)425 (50)
 II3733 (27)219 (26)
 III1055 (8)142 (17)
 IV271 (2)70 (8)
  • Data presented as mean±SD, except otherwise indicated.

  • AVA, aortic valve area; LVOT, left ventricular outflow tract.