Table 3

Risk factors associated with mortality

SurvivalUnivariate analysisMultivariate analysis
176 events, 2732 patientsHR (95% CI), p valueC-statHR (95% CI), p value
Male gender0.84 (0.62 to 1.13), 0.240.53
Ethnicity
 Whiteref0.51
 Black1.69 (0.69 to 4.14), 0.25
 Asian1.17 (0.55 to 2.53), 0.68
 Other/non-stated0.98 (0.71 to 1.35), 0.91
Deprivation
 Less deprived 20%ref0.54
 Less deprived 20%–50%0.78 (0.51 to 1.20), 0.27
 More deprived 20%–50%0.95 (0.63 to 1.44), 0.81
 Most deprived <20%0.75 (0.45 to 1.23), 0.25
Age at first operation
 <16 yearsref0.54ref
 ≥16 years2.04 (1.35 to 3.09), 0.001*1.63 (1.02 to 2.59), 0.04*
Time period
 Before 2006ref0.50ref
 2006 or after1.10 (0.78 to 1.57), 0.580.67 (0.42 to 1.07), 0.10
Complexity of diagnosis
 Moderateref0.54ref
 Severe1.58 (1.06 to 2.36), 0.03*1.50 (0.96 to 2.33), 0.07
Procedures
 Homograft valveref0.53ref
 Xenograft valve1.26 (0.88 to 1.79), 0.211.08 (0.66 to 1.76), 0.77
 Mechanical valve1.49 (0.94 to 2.34), 0.091.34 (0.76 to 2.36), 0.32
 Percutaneous valve1.83 (1.10 to 3.05), 0.02*2.37 (1.26 to 4.48), 0.008*
  • * p value ≤  0.05

  • C statistics for the multivariate analysis were 0.58.