Baseline characteristics
| APACE cohort | High-STEACS cohort | |||||||
| Unstable angina | NSTEMI | P value UA vs NSTEMI | NCCP | Unstable angina | NSTEMI | P value UA vs NSTEMI | NCoCP | |
| n=366 | n=622 | n=2154 | n=137 | n=651 | n=3951 | |||
| Age (years) | 69 (59, 76) | 73 (60, 80) | 0.001 | 55 (44, 68) | 72 (63, 79) | 71 (60, 81) | 0.915 | 63 (51, 76) |
| Sex—male | 298 (81.4) | 457 (73.5) | 0.005 | 1415 (65.7) | 89 (65.0) | 384 (59.0) | 0.229 | 2205 (55.8) |
| Risk factors | ||||||||
| Hypertension | 332 (90.7) | 488 (78.5) | <0.001 | 1030 (47.8) | 61 (47.7) | 262 (42.8) | 0.364 | 1070 (31.3) |
| Hypercholesterolaemia | 300 (82) | 417 (67) | <0.001 | 830 (38.5) | 65 (50.8) | 230 (37.6) | 0.008 | 828 (24.2) |
| BMI (kg/m2) | 27 (24, 30) | 26 (24, 29) | 0.017 | 26 (24, 29) | ||||
| Diabetes mellitus | 94 (25.8) | 139 (22.5) | 0.227 | 213 (10) | 37 (28.9) | 114 (18.7) | 0.013 | 518 (15.1) |
| Active smoker | 68 (18.6) | 150 (24.1) | 0.047 | 613 (28.5) | 29 (37.2) | 126 (30.5) | 0.484 | 529 (24.7) |
| Positive family history | 163 (46.2) | 245 (41.6) | 0.175 | 816 (39.8) | ||||
| Medical history | ||||||||
| Coronary artery disease | 268 (73.2) | 306 (49.2) | <0.001 | 500 (23.2) | 97 (75.8) | 275 (44.9) | <0.001 | 1019 (29.7) |
| Prior myocardial infarction | 193 (52.7) | 232 (37.3) | <0.001 | 351 (16.3) | 53 (41.4) | 172 (28.1) | 0.004 | 571 (16.7) |
| Prior coronary revascularisation | 238 (65) | 241 (38.7) | <0.001 | 417 (19.4) | 48 (37.5) | 149 (24.3) | 0.003 | 456 (13.3) |
| Vital parameters at admission | ||||||||
| Systolic blood pressure (mm Hg) | 143 (130, 159) | 142 (126, 160) | 0.599 | 140 (126, 154) | 137 (120, 158) | 139 (121, 156) | 0.443 | 136 (121, 153) |
| Heart rate (beats/min) | 69 (61, 80) | 78 (67, 90) | <0.001 | 76 (66, 88) | 69.00 (64, 77) | 76.50 (65, 90) | <0.001 | 78 (66, 92) |
| Breathing rate (breaths/min) | 16 (14, 19) | 16 (14, 20) | 0.356 | 16 (14, 19) | ||||
| Electrocardiography | ||||||||
| ST-segment depression | 34 (9.4) | 164 (26.9) | <0.001 | 56 (2.6) | 7 (5.2) | 128 (20.8) | <0.001 | 167 (5.0) |
| T-wave inversion | 71 (19.4) | 140 (22.5) | 0.261 | 143 (6.6) | 19 (13.9) | 143 (22.0) | 0.017 | 353 (8.9) |
APACE, Advantageous Predictors of Acute Coronary Syndromes Evaluation; BMI, body mass index; High-STEACS, High-Sensitivity Troponin in the Evaluation of Patients With Acute Coronary Syndrome; NCCP, non-cardiac chest pain; NCoCP, non-coronary chest pain; NSTEMI, non-ST-elevation myocardial infarction.