Table 3

Pregnancy in hypertrophic cardiomyopathy: symptoms, complications, delivery and mortality

AuthorYearWomenPregnanciesArrhythmiaSyncopeHFCVAChest painCSAbortionDeaths
Turner et al 44 19689132 (22) tachycardia.1 (11)5 (56) dyspnoea.
2 (22) HF.
NA2 (22)4 (44)3 (33)0
Oakley et al 45 19792354NANA10 (43) dyspnoea.2 (9)10 (43)1 (1.8) medical.
10 (18) spontaneous.
0
Siu et al 11 20019NA1 VTNANANANANANA0
Autore et al 29 20021001991/40 (2.5) AF.1/40, (2.5) during labour6/40 (15) dyspnoea/HF.NANA15/40 (38)NA2/100
(2)
Thaman et al 46 20031272719 (7) palpitations.2 (1.6)6 (5) dyspnoea.
2 (1.6) HF postpartum.
NA12 (9)19 (15)NA0
Avila et al 43 200315153 (2) AF+1 NA.05 (33)05 (33)NANA0
Walker et al 47 20071011NANANANANA2 (20) obstetric.00
Avila et al 48 200723232 (9) AF.
1 (4) SVT.
NA7 (30)1 (4)NA12 (52) obstetric.NA0
Schuler et al 49 20128121 (12) SVT.
1 (12) VT-antitachycardia pacing.
1 (12) non-sustained VT.
NA2 (24)1 (12)NA4 (50)1 (12) foetal reason.0
Sikka et al 4 2014443 (75) palpitations.NA1 (25) HF.
3 (75) dyspnoea.
1 (25)000
Tanaka et al 32 201423271 (4) VT
6 (26) non-sustained VT.
6 (26) PVC.
NA2 (8) worsening NYHA class.NANA9 (33)4 (15) pregnancies terminated, cardiac reasons.0
Ashikhmina et al 50 201514236 (43) palpitations.5 (36) syncope.
2 (14) presyncope.
7 (50) dyspnoea.
3 (21) HF postpartum.
2 (14)11 (79)NA0
Lima et al 51 201552NANANA7 (13)0NA25 (48)NA0
Goland et al 30 201760606 (10) VT.
1 (17) AF.
NA9 (15)0NA36 (60)00
Billebau et al 7 201822281 (4) VT.NA3 (14)NANA2 (7) cardiac.NA1 (4)
  • All values are n (%).

  • AF, atrial fibrillation; CS, caesarean section; CVA, cardiovascular accident; HF, heart failure; NA, not available; NYHA, New York Heart Association functional class; PVC, premature ventricular contraction; SVT, supraventricular tachycardia; VT, ventricular tachycardia.