Table 3

Univariable and multivariable associations for B-type natriuretic peptide

	Univariable regression analysis			Multivariable regression analysis*: r²=0.18
	Coefficient	95% CI	P value	Coefficient	95% CI	P value
Age (per 10 years)	0.6	0.49 to 0.71	<0.001	0.54	0.41 to 0.67	<0.001
Male	−0.32	−0.54 to −0.10	0.005	−0.33	−0.60 to −0.06	0.016
Hypertension	0.31	0.09 to 0.54	0.007
Hyperlipidaemia	0.55	0.33 to 0.77	<0.001
Diabetes	−0.22	−0.58 to 0.14	0.23
Documented CAD	0.74	0.35 to 1.12	<0.001	0.46	0.09 to 0.84	0.016
Family history of CAD	−0.07	−0.30 to 0.15	0.52
Ex-smoker	0.22	−0.03 to 0.47	0.082
Current smoker	−0.24	−0.54 to 0.05	0.11
BMI (log₂)	−0.45	−0.87 to −0.03	0.035
Systolic blood pressure (log₂)	0.61	0.06 to 1.16	0.028
Diastolic blood pressure (log₂)	−0.36	−0.90 to 0.18	0.19
CT-adapted Leaman score (log₂)	0.2	0.13 to 0.26	<0.001	0.12	0.05 to 0.19	0.001
Indexed left ventricular mass (log₂)	−0.3	−0.71 to 0.11	0.15
Indexed left ventricular volume (log₂)	0.3	−0.15 to 0.74	0.19	1.24	0.79 to 1.69	<0.001
Creatinine (log₂)	−0.39	−0.71 to −0.06	0.019	−0.42	−0.74 to −0.11	0.008

*All covariates were included in the final multivariable linear regression model; only those with p<0.05 are presented. Full modelling is presented in online supplementary table 2.
BMI, body mass index; CAD, coronary artery disease.