Univariable regression analysis | Multivariable regression analysis*: r2=0.30 | |||||
Coefficient | 95% CI | P value | Coefficient | 95% CI | P value | |
Age (per 10 years) | 0.37 | 0.30 to 0.44 | <0.001 | 0.33 | 0.25 to 0.41 | <0.001 |
Male | 0.60 | 0.47 to 0.73 | <0.001 | 0.25 | 0.10 to 0.40 | 0.002 |
Hypertension | 0.49 | 0.35 to 0.63 | <0.001 | 0.17 | 0.04 to 0.30 | 0.011 |
Hyperlipidaemia | 0.29 | 0.15 to 0.43 | <0.001 | |||
Diabetes | 0.19 | −0.04 to 0.41 | 0.11 | |||
Documented CAD | 0.40 | 0.16 to 0.64 | 0.001 | |||
Family history of CAD | −0.23 | −0.37 to −0.10 | 0.001 | |||
Ex-smoker | 0.03 | −0.12 to 0.19 | 0.68 | |||
Current smoker | −0.15 | −0.34 to 0.03 | 0.10 | |||
BMI (log2) | 0.15 | −0.11 to 0.41 | 0.27 | 0.24 | 0.00 to 0.47 | 0.048 |
Systolic blood pressure (log2) | 1.16 | 0.83 to 1.49 | <0.001 | 0.52 | 0.17 to 0.87 | 0.004 |
Diastolic blood pressure (log2) | 0.49 | 0.16 to 0.82 | 0.004 | |||
CT-adapted Leaman score (log2) | 0.19 | 0.16 to 0.23 | <0.001 | 0.06 | 0.02 to 0.10 | 0.007 |
Indexed left ventricular mass (log2) | 1.37 | 1.13 to 1.61 | <0.001 | 0.92 | 0.64 to 1.20 | <0.001 |
Indexed left ventricular volume (log2) | 0.01 | −0.27 to 0.28 | 0.96 | |||
Creatinine (log2) | 0.41 | 0.22 to 0.61 | <0.001 |
*All covariates were included in the final multivariable linear regression model; only those with p<0.05 are presented. Full modelling is presented in online supplementary table 1.
BMI, body mass index; CAD, coronary artery disease.