Cox proportional hazards for secondary endpoints according to troponin adjusted for GRACE discharge risk
| ≤5 ng/L | 6 ng/L–99th centile | >99th centile* | |||
| (n=795) | (n=815) | HR (95% CI) | (n=166) | HR (95% CI) | |
| Cardiovascular death | 34 (4.3) | 119 (14.6) | 2.52 (1.65 to 3.85) | 49 (29.5) | 4.87 (2.96 to 7.99) |
| Cardiac death | 25 (3.1) | 92 (11.3) | 2.51 (1.54 to 4.07) | 43 (25.9) | 5.50 (3.17 to 9.57) |
| All-cause death | 81 (10.2) | 216 (26.5) | 1.90 (1.44 to 2.51) | 78 (47.0) | 3.34 (2.36 to 4.73) |
| Cardiovascular death or non-fatal myocardial infarction | 123 (15.5) | 236 (29.0) | 1.58 (1.25 to 2.01) | 74 (44.6) | 2.51 (1.82 to 3.44) |
| Non-cardiovascular death | 47 (5.9) | 97 (11.9) | 1.48 (1.02 to 2.16) | 29 (17.5) | 2.30 (1.38 to 3.81) |
| Fatal or non-fatal myocardial infarction | 102 (12.8) | 168 (20.6) | 1.38 (1.06 to 1.80) | 53 (31.9) | 2.23 (1.55 to 3.21) |
| Heart failure hospitalisation | 53 (6.7) | 165 (20.2) | 2.09 (1.48 to 2.95) | 66 (39.8) | 3.98 (2.62 to 6.05) |
| Non-fatal stroke | 45 (5.7) | 68 (8.3) | 1.12 (0.73 to 1.71) | 13 (7.8) | 0.98 (0.48 to 2.02) |
*99th centile determined using sex-specific cut points (women>16 ng/L, men>34 ng/L).
Values are n (%) unless otherwise stated.
GRACE, Global Registry of Acute Coronary Events.