Bivariable and multivariable association between patient characteristics and mortality
| Bivariable | Multivariable | |||
| Mortality HR (95% CI) | P value | Mortality HR (95% CI) | P value | |
| Age, per 10 years increase | 1.18 (1.09 to 1.29) | <0.001 | 1.23 (1.12 to 1.35) | <0.001 |
| Male gender | 1.11 (0.90 to 1.38) | 0.342 | – | |
| Atrial fibrillation/flutter | 1.14 (0.88 to 1.46) | 0.316 | – | |
| Coronary artery disease | 1.05 (0.83 to 1.34) | 0.661 | – | |
| Peripheral artery disease | 1.31 (1.04 to 1.65) | 0.021 | 1.17 (0.93 to 1.48) | 0.189 |
| Diabetes mellitus | 1.27 (1.02 to 1.58) | 0.033 | 1.21 (0.97 to 1.52) | 0.088 |
| Hypertension | 1.21 (0.90 to 1.65) | 0.210 | – | |
| Chronic lung disease | 1.18 (0.94 to 1.47) | 0.156 | 1.12 (0.90 to 1.41) | 0.32 |
| Hyperlipidaemia | 1.09 (0.87 to 1.37 | 0.472 | – | |
| Infective endocarditis | 0.90 (0.52 to 1.57) | 0.706 | – | |
| Pulmonary embolism | 0.79 (0.49 to 1.27 | 0.324 | – | |
| Right ventricular systolic dysfunction | ||||
| Normal | Reference | 0.020 | Reference | 0.001 |
| Mild | 1.25 (0.91 to 1.73) | 1.28 (0.92 to 1.77) | 0.141 | |
| Moderate | 1.29 (0.95 to 1.75) | 1.39 (1.01 to 1.90) | 0.044 | |
| Severe | 1.75 (1.25 to 2.44) | 2.00 (1.40 to 2.80) | <0.001 | |
| Left heart disease | 1.34 (1.04 to 1.74) | 0.026 | 1.29 (0.99 to 1.68) | 0.058 |
| Evidence of pulmonary hypertension | 1.03 (0.79 to 1.35) | 0.817 | – | |
| Previous cardiac device | 1.28 (1.03 to 1.58) | 0.028 | 1.17 (0.94 to 1.46) | 0.165 |
| Previous open-heart surgery | 1 (0.80 to 1.24) | 0.992 | – | |
| Tricuspid valve surgery | 0.40 (0.25 to 0.64) | <0.001 | 0.44 (0.27 to 0.71) | 0.001 |