Table 4

Univariate associations with cardiovascular mortality

Male (n=425)Female (n=249)Interaction p value
ParameterHR95% CIP valueHR95% CIP value
 Age1.091.05 to 1.14 < 0.001 1.061.02 to 1.10 0.003 0.336
 BMI1.020.95 to 1.100.5210.940.88 to 1.010.0790.094
 Hypertension1.080.56 to 2.080.8240.980.50 to 1.920.9430.837
 Diabetes1.991.02 to 3.89 0.044 2.131.04 to 4.38 0.039 0.891
 AF4.051.99 to 8.23 < 0.001 2.291.07 to 4.91 0.033 0.283
 BAV0.070.01 to 0.48 0.007 0.85 0.33 to 2.210.745 0.023
 Previous MI1.580.66 to 3.800.3091.640.50 to 5.380.4180.962
 Previous PCI/CABG1.030.45 to 2.360.9453.561.73 to 7.32 0.001 0.027
 Known CAD1.760.91 to 3.400.0923.151.55 to 6.40 0.001 0.237
 ACE-I/ ARB2.431.19 to 4.94 0.014 0.930.44 to 1.940.8380.065
 BB1.610.84 to 3.110.1521.310.66 to 2.600.4400.666
 Statin1.660.78 to 3.530.1901.070.53 to 2.160.8440.407
 STS score1.271.17 to 1.39 < 0.001 1.151.06 to 1.24 < 0.001 0.080
 EuroSCORE1.111.04 to 1.18 0.003 1.131.07 to 1.20 < 0.001 0.627
Echo data
 PPG0.990.98 to 1.010.4511.000.98 to 1.020.8650.661
 MPG0.990.96 to 1.020.4251.000.97 to 1.020.7050.764
 AVAI0.040.00 to 1.730.0921.340.06 to 27.670.8510.148
CMR data
 LVEDVI1.010.99 to 1.020.4421.011.00 to 1.030.1690.586
 LVESVI1.011.00 to 1.02 0.014 1.021.01 to 1.04 0.006 0.414
 LVSVI0.950.92 to 0.98 < 0.001 0.970.93 to 1.000.0500.423
 LVEF0.970.95 to 0.98 < 0.001 0.960.94 to 0.98 < 0.001 0.665
 RVEDVI1.010.99 to 1.030.4431.000.98 to 1.020.7510.446
 RVEF0.960.93 to 0.98 0.001 0.980.95 to 1.000.0760.358
 LAVI1.021.01 to 1.03 0.005 1.021.00 to 1.03 0.030 0.673
 LVMI1.000.99 to 1.020.9321.010.99 to 1.020.4090.599
 LV mass/volume0.640.21 to 2.000.4440.770.19 to 3.120.7120.844
 LGE presence9.852.36 to 41.15 0.002 2.811.34 to 5.87 0.006 0.126
 LGE non-infarct1.670.85 to 3.310.1391.290.62 to 2.700.4940.614
 LGE infarct2.561.29 to 5.11 0.008 3.941.81 to 8.62 0.001 0.418
 LGE (g) (FWHM)1.031.00 to 1.06 0.032 1.101.04 to 1.17 0.001 0.029
 LGE (%) (FWHM)1.071.01 to 1.14 0.019 1.151.07 to 1.22 < 0.001 0.151
  • Abbreviations are as per table 1.Hazard ratios are per unit of the variable. Interaction p value is for interaction of variable with sex, which was included in the model.

  • SAVR, surgical aortic valve replacement; TAVR, transcatheter aortic valve replacement.