Table 2

Imaging results

All
(n=46)
Stable atherosclerosis
(n=27)
Matched stable atherosclerosis (n=19)*Unstable atherosclerosis
(n=19)
P value†
18F-Fluciclatide PET uptake
 SVC (SUVmean )2.73 (2.35–3.05)2.66 (2.21–2.96)2.47 (2.07–2.78)2.88 (2.61–3.26)0.01
 Whole aorta (mean SUVmax )3.65 (3.04–4.01)3.43 (2.95–3.81)3.04 (2.86–3.61)3.87 (3.46–4.12)0.002
 Whole aorta (mean TBRmax )1.31 (1.20–1.39)1.29 (1.20–1.38)1.25 (1.19–1.36)1.32 (1.17–1.42)0.32
 Ascending aorta (mean TBRmax )1.32 (1.23–1.37)1.27 (1.23–1.36)1.24 (1.20–1.34)1.33 (1.18–1.39)0.10
 Aortic Arch (mean TBRmax )1.28 (1.16–1.40)1.27 (1.14–1.37)1.21 (1.13–1.33)1.29 (1.25–1.44)0.02
 Descending aorta (mean TBRmax )1.31 (1.19–1.42)1.30 (1.23–1.41)1.26 (1.17–1.41)1.32 (1.12–1.45)0.97
CT calcium score
 Whole aorta (AU)95 (0–852)326 (11–1114)36 (0–469)19 (0–483)0.85
 Ascending aorta (AU)0 (0–11)0 (0–46)0 (0–0)0 (0–0)0.15
 Aortic arch (AU)29 (0–352)102 (0–586)13 (0–469)0 (0–263)0.76
 Descending aorta (AU)7.5 (0–78)0 (0–123)0 (0–123)8 (0–71)0.43
CTA plaque analysis (descending aorta)
 Mean wall thickness (% vessel diameter)9.1 (6.5–12.8)8.0 (6.3–10.0)8.1 (6.3–9.8)12.8 (8.6–18.4)0.009
 Plaque burden (% total volume)8.3 (6.1–11.4)7.4 (6.0–9.1)7.5 (5.9–8.9)11.4 (7.9–15.6)0.008
  • Data are presented as median (IQR).

  • CTA, computed tomography angiography.

  • * Stable group subjects paired to equivalent calcium score in unstable group.

  • † P values are quoted for comparisons between matched stable and unstable groups.

  • AU, arbitrary units; CTA, Computed Tomography Angiography; PET, positron emission tomography; SUV, standard uptake value; SVC, superior vena cava; TBR, tissue-to-background ratio.