Patient demographics/characteristics, symptoms and cardiac medications based on WHO body mass index categories
| Underweight BMI <18.5 n=56 (1%) | Normal 18.5–24.9 n=1459 (16%) | Overweight 25.0–29.9 n=3135 (35%) | Obese 1 30.0–34.9 n=2463 (28%) | Obese 2 35.0–39.9 n=1170 (13%) | Obese 3 ≥40 n=606 (7%) | P value | |
| Age, years* | 61.2 (8.57) | 62.7 (8.94) | 61.3 (8.48) | 60.3 (7.86) | 59.1 (7.42) | 58.5 (6.84) | <0.001 |
| Female sex | 42/56 (75.0) | 899/1459 (61.6) | 1499/3135 (47.8) | 1216/2463 (49.4) | 655/1170 (56.0) | 367/606 (60.6) | <0.001 |
| Race | <0.001 | ||||||
| White | 49/55 (89.1) | 1250/1445 (86.5) | 2655/3111 (85.3) | 2066/2446 (84.5) | 973/1154 (84.3) | 476/603 (78.9) | |
| Black | 4/55 (7.3) | 107/1445 (7.4) | 272/3111 (8.7) | 299/2446 (12.2) | 154/1154 (13.3) | 112/603 (18.6) | |
| Asian | 1/55 (1.8) | 65/1445 (4.5) | 118/3111 (3.8) | 29/2446 (1.2) | 5/1154 (0.4) | 2/603 (0.3) | |
| Ethnicity | 0.063 | ||||||
| Hispanic or Latino | 3/55 (5.5) | 82/1446 (5.7) | 253/3118 (8.1) | 196/2448 (8.0) | 85/1163 (7.3) | 41/605 (6.8) | |
| Not Hispanic or Latino | 52/55 (94.5) | 1364/1446 (94.3) | 2865/3118 (91.9) | 2252/2448 (92.0) | 1078/1163 (92.7) | 564/605 (93.2) | |
| Cardiac risk factors | |||||||
| Hypertension | 31/56 (55.4) | 698/1459 (47.8) | 1855/3135 (59.2) | 1754/2463 (71.2) | 915/1170 (78.2) | 506/606 (83.5) | <0.001 |
| Diabetes | 6/56 (10.7) | 153/1459 (10.5) | 417/3135 (13.3) | 645/2463 (26.2) | 382/1170 (32.6) | 281/606 (46.4) | <0.001 |
| Dyslipidaemia | 27/56 (48.2) | 894/1459 (61.3) | 2160/3135 (68.9) | 1744/2463 (70.8) | 801/1170 (68.5) | 391/606 (64.5) | <0.001 |
| Smoker (ever/never) | 35/56 (62.5) | 798/1459 (54.7) | 1581/3134 (50.4) | 1282/2463 (52.1) | 565/1170 (48.3) | 282/606 (46.5) | <0.001 |
| Family history of premature CAD | 19/55 (34.5) | 458/1451 (31.6) | 981/3129 (31.4) | 765/2455 (31.2) | 396/1167 (33.9) | 197/605 (32.6) | 0.610 |
| Sedentary lifestyle | 23/56 (41.1) | 570/1456 (39.1) | 1348/3130 (43.1) | 1247/2459 (50.7) | 699/1170 (59.7) | 414/606 (68.3) | <0.001 |
| Metabolic syndrome | 4/56 (7.1) | 118/1459 (8.1) | 430/3135 (13.7) | 1564/2463 (63.5) | 806/1170 (68.9) | 443/606 (73.1) | <0.001 |
| Primary presenting symptom | |||||||
| Chest pain | 47/56 (83.9) | 1087/1458 (74.6) | 2292/3134 (73.1) | 1801/2461 (73.2) | 815/1168 (69.8) | 421/606 (69.5) | 0.011 |
| Dyspnoea | 6/56 (10.7) | 188/1458 (12.9) | 441/3134 (14.1) | 383/2461 (15.6) | 203/1168 (17.4) | 117/606 (19.3) | <0.001 |
| Medication use | |||||||
| Aspirin | 15/55 (27.3) | 582/1366 (42.6) | 1302/2981 (43.7) | 1108/2381 (46.5) | 526/1135 (46.3) | 277/589 (47.0) | 0.006 |
| Statin | 15/55 (27.3) | 546/1366 (40.0) | 1382/2981 (46.4) | 1160/2381 (48.7) | 524/1135 (46.2) | 275/589 (46.7) | <0.001 |
| Beta-blocker | 17/55 (30.9) | 284/1366 (20.8) | 658/2981 (22.1) | 645/2381 (27.1) | 319/1135 (28.1%) | 188/589 (31.9) | <0.001 |
| ACEi or ARB | 16/55 (29.1) | 397/1366 (29.1) | 1110/2981 (37.2) | 1183/2381 (49.7) | 642/1135 (56.6) | 377/589 (64.0) | <0.001 |
Data are n/N (%) except where indicated.
*Mean (SD).
ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; BMI, body mass index; CAD, coronary artery disease.