Phenogroup (n) | Generalised characteristics | Primary events per 100 patient-years* |
1 (n=30) | Younger, risk factors such as hypertension, CAD and diabetes, larger left ventricular volumes, and CKD | 33 |
2 (n=40) | Older, less hypertrophy but worse left ventricular and right ventricular systolic function and more severe HF, and notably high prevalence of COPD | 40 |
3 (n=48) | Younger, male, obesity, less left and right diastolic and systolic function, and milder HF | 11 |
4 (n=52) | Male, hypertension, left ventricular hypertrophy, left atrial enlargement and AF | 19 |
5 (n=101) | Older, female, hypertension, CAD, large left side but good right ventricular function | 21 |
6 (n=49) | Older, female, low BMI, hypertension, AF and right-sided failure | 27 |
*Derived from events to mid-term time point at 18 months.
AF, atrial fibrillation; BMI, body mass index; CAD, coronary artery disease; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; HF, heart failure.