Table 1

Studies reporting age-specific and sex-specific performance parameters for patients with acute coronary syndrome published after 2010

StudyNumber of patientsPCI rateOutcome of interest
Pilgrim et al 12 4723 patients with STEMI
1319 women
72% W
79% M
Door-to-balloon > 90 min
W≤65 y vs M≤65 y: OR adjusted 1.47; 95% CI: 1.13 to 1.91
W>65 y vs M≤65 y: OR adjusted 1.57; 95% CI: 1.27 to 1.93
M>65 y vs M≤65 y: OR adjusted 1.66; 95% CI: 1.40 to 1.95
Risk of PCI withhold
W≤65 y vs M≤65 y: OR adjusted 0.88; 95% CI: 0.53 to 1.45
W>65 y vs M≤65 y: OR adjusted 9.31; 95% CI: 7.37 to 11.75
M>65 y vs M≤65 y: OR adjusted 4.91; 95% CI: 3.93 to 6.13
D’Onofrio et al 13 1238 patients with STEMI
761 women all <55 years
91% W
88% M
Door-to-balloon exceeds guideline recommended timeframe
W vs M: OR 1.65; 95% CI: 1.27 to 2.16
Udell et al 5 104 817 patients with AMI
(29% STEMI)
41 264 women
51% of all patients with STEMI Door-to-balloon 90 min
W<55 y vs M<55 y: OR 0.80; 95% CI: 0.69 to 0.93
W55–64.9 y vs M55–64.9 y: OR 0.81; 95% CI: 0.70 to 0.92
W65–74.9 y vs M65–74.9 y: OR 0.93; 95% CI: 0.79 to 1.10
W≥75 y vs M≥75 y: OR 0.97; 95% CI: 0.83 to 1.14
  • AMI, acute myocardial infarction; M, men; NSTEMI, non-STEMI; PCI, percutaneous coronary intervention; STEMI, ST-segment elevation myocardial infarction; W, women; y, years.