Maternal and fetal outcomes in aortic stenosis by severity
| Outcome | Severity | Studies | Events | Total patients | Estimate, % | 95% CI | Tau2 | I2 % | |
| Maternal | Death | Moderate | 4 | 0 | 81 | NA | NA | NA | NA |
| Severe | 7 | 2 | 103 | 2% | 0% to 5% | <0.01 | 0 | ||
| Pulmonary Oedema | Moderate | 3 | 1 | 19 | 8% | 0% to 20% | <0.01 | 0 | |
| Severe | 6 | 8 | 69 | 9% | 2% to 15% | <0.01 | 0 | ||
| NYHA III-IV | Moderate | 3 | 6 | 74 | 8% | 2% to 15% | <0.01 | 0 | |
| Severe | 5 | 13 | 84 | 22% | 5% to 40% | 0.03 | 83 | ||
| New/Recurrent Paroxysmal Arrhythmias | Moderate | 2 | 1 | 68 | 2% | 0% to 5% | <0.01 | 0 | |
| Severe | 5 | 3 | 87 | 4% | 0% to 7% | <0.01 | 0 | ||
| Surgical Intervention | Moderate | 4 | 1 | 81 | 2% | 0% to 5% | <0.01 | 0 | |
| Severe | 7 | 0 | 103 | NA | NA | NA | NA | ||
| Percutaneous intervention | Moderate | 4 | 0 | 81 | NA | NA | NA | NA | |
| Severe | 7 | 2 | 103 | 4% | 0% to 7% | <0.01 | 0 | ||
| Fetal | Stillbirth | Moderate | 4 | 0* | 81 | NA | NA | NA | NA |
| Severe | 7 | 1 | 103 | 2% | 0% to 5% | <0.01 | 0 | ||
| Neonatal Death | Moderate | 4 | 0 | 81 | NA | NA | NA | NA | |
| Severe | 7 | 1 | 103 | 3% | 0% to 6% | <0.01 | 0 | ||
| Pre-term Birth | Moderate | 4 | 11 | 81 | 13% | 6% to 20% | <0.01 | 0 | |
| Severe | 7 | 17 | 103 | 14% | 4% to 24% | 0.01 | 83 | ||
| SGA | Moderate | 3 | 4 | 75 | 5% | 0% to 13% | <0.01 | 20 | |
| Severe | 6 | 9 | 97 | 7% | 1% to 14% | <0.01 | 42 |
*2 miscarriages were reported before 24 weeks but the exact gestation at the time of fetal demise was not specified. See text for details.
NA, Not applicable; NYHA, New York Heart Association; SGA, Small for gestational age.