Table 2

Incidence and HR of stroke, IS, HS and AMI in patients with atrial flutter compared with those without heart failure

OutcomeWithout heart failureWith heart failure
(n=12 179)(n=12 179)
Stroke  
 Follow-up time
 (year, mean±SD)		6.54±3.855.70±3.95
 Event9261227
 Person-years79 67969 368
 Rate*11.617.7
 Crude HR (95% CI)1 (Reference)1.51 (1.38 to 1.64)***
 Adjusted HR†(95% CI)1 (Reference)1.59 (1.46 to 1.74)***
IS  
 Event7571009
 Rate*9.5014.6
 Crude HR (95% CI)1 (Reference)1.51 (1.38 to 1.66)***
 Adjusted HR†(95% CI)1 (Reference)1.59 (1.45 to 1.75)***
HS  
 Event169218
 Rate*2.123.14
 Crude HR (95% CI)1 (Reference)1.48 (1.21 to 1.81)***
 Adjusted HR†(95% CI)1(Reference)1.55 (1.27 to 1.90)***
AMI  
 Follow-up time
 (year, mean±SD)		6.77±3.835.95±3.98
 Event97299
 Person-years82 50072 470
 Rate*1.184.13
 Crude HR (95% CI)1 (Reference)3.45 (2.74 to 4.33)***
 Adjusted HR†(95% CI)1 (Reference)3.60 (2.86 to 4.53)***

  • ***p<0.001.

  • *Rate, incidence rate, per 1000 person-years; crude HR, relative HR.

  • †Adjusted all variables listing in table 1.

  • AMI, acute myocardial infarction; HS, haemorrhagic stroke; IS, ischaemic stroke.