Baseline characteristics of patients with mitral stenosis
| Total (n=42 075) | MS with AF (n=27 824) | MS without AF (n=14 251) | P value | |
| Age (years) (mean±SD) | 60.7±13.5 | 61.4±12.3 | 59.3±15.4 | <0.0001 |
| Female gender, n (%) | 28 772 (68.4) | 18 734 (67.3) | 10 038 (70.4) | <0.0001 |
| Hypertension, n (%) | 38 335 (91.1) | 26 424 (95.0) | 11 911 (83.6) | <0.0001 |
| Diabetes mellitus, n (%) | 26 040 (61.9) | 18 201 (65.4) | 7839 (55.0) | <0.0001 |
| Previous stroke, n (%) | 12 252 (29.1) | 9586 (34.5) | 2666 (18.7) | <0.0001 |
| Congestive heart failure | 27 666 (65.8) | 21 047 (75.6) | 6619 (46.5) | <0.0001 |
| Previous vascular disease* | 19 724 (46.9) | 13 098 (47.1) | 6626 (46.5) | 0.26 |
| CHA2DS2-VASc (mean±SD) | 4.2±1.8 | 4.4±1.7 | 3.8±1.9 | <0.0001 |
| COPD | 9714 (23.1) | 6986 (25.1) | 2728 (19.1) | <0.0001 |
| CKD | 4126 (9.8) | 3025 (10.9) | 1101 (7.7) | <0.0001 |
| Drugs | ||||
| Aspirin | 27 745 (65.9) | 18 638 (67.0) | 9107 (63.9) | <0.0001 |
| Clopidogrel | 12 942 (30.8) | 9002 (32.4) | 3940 (27.7) | <0.0001 |
| Cilostazol | 4570 (10.9) | 3041 (10.9) | 1529 (10.7) | 0.53 |
| Ticlopidine | 932 (2.2) | 607 (2.2) | 325 (2.3) | 0.51 |
| Vitamin K antagonist | 30 344 (72.1) | 24 975 (89.8) | 5369 (37.7) | <0.0001 |
*Previous vascular diseases defined as prior myocardial infarction, peripheral artery disease or aortic plaque.
AF, atrial fibrillation; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; MS, mitral stenosis.