Table 4

Physiology for all patients with Combowire data including post-PCI Combowire results pressure following Core Laboratory analysis (n=89/93), flow and resistance data for all randomised patients with Combowire data according to treatment group

Baseline invasive physiology for entire cohort
NMinimumMaximumMean (SD)
FFR890.750.820.78 (0.02)
HMR890.96.92.10 (0.84)
HSR890.152.000.52 (0.25)
CFVR891.35.02.41 (0.75)
By randomised group
NMeanSD
FFROMT380.780.02
PCI510.780.02
HMROMT382.210.74
PCI512.010.91
HSROMT380.550.21
PCI510.500.27
CFVROMT382.350.72
PCI512.450.77
Invasive physiology pre-PCI and post-PCI
Pre-PCIPost-PCINP value
FFR0.77 (0.02)0.90 (0.06)410.001
HMR2.07 (0.98)2.31 (0.95)410.02
HSR0.51 (0.29)0.20 (0.18)400.001
CFVR2.34 (0.73)2.28 (0.69)400.548
  • CFVR, coronary flow velocity reserve; FFR, fractional flow reserve; HMR, hyperaemic microvascular resistance; HSR, Hyperaemic Stenosis Resistance Index; N, total number of patients; OMT, optimal medical therapy group; PCI, percutaneous coronary intervention with medical therapy group.