Table 4

Risk of ischaemic heart disease (IHD) and myocardial infarction (MI) by exposure status

IHDMI
MaleFemaleMaleFemale
HR (95% CI)HR (95% CI)HR (95% CI)HR (95% CI)
ILD1.66 (1.40 to 1.98)1.36 (1.03 to 1.79)1.55 (1.31 to 1.84)1.49 (1.16 to 1.91)
PS1.13 (0.78 to 1.63)0.88 (0.55 to 1.41)1.55 (1.13 to 2.14)0.89 (0.56 to 1.42)
PF1.81 (1.50 to 2.18)1.67 (1.22 to 2.30)1.51 (1.24 to 1.83)1.80 (1.36 to 2.38)
 Age (years)IHD (HR (95% CI))MI (HR (95% CI))
ILDPSPFILDPSPF
<501.61 (0.92 to 2.81)1.49 (0.83 to 2.66)1.89 (0.56 to 6.33)1.72 (1.04 to 2.83)1.83 (1.10 to 3.05)0.87 (0.21 to 3.66)
50–591.16 (0.73 to 1.82)0.75 (0.41 to 1.36)2.05 (1.13 to 3.72)1.48 (0.95 to 2.29)1.35 (0.80 to 2.28)1.47 (0.78 to 2.74)
60–691.92 (1.46 to 2.52)0.88 (0.51 to 1.53)2.40 (1.79 to 3.22)1.79 (1.35 to 2.38)0.62 (0.32 to 1.22)2.35 (1.74 to 3.16)
70–791.71 (1.35 to 2.17)0.81 (0.36 to 1.81)1.84 (1.45 to 2.35)1.77 (1.40 to 2.23)1.35 (0.72 to 2.54)1.79 (1.40 to 2.29)
>801.08 (0.73 to 1.61)0.82 (0.11 to 6.18)1.10 (0.73 to 1.64)0.91 (0.64 to 1.28)1.30 (0.38 to 4.39)0.89 (0.62 to 1.27)
  • All analyses adjusted for CKD, HTN, DM, HLD, BMI, exposure to smoking and alcohol, IMD, family history of cardiovascular disease and exposure to antihypertensive, antiplatelet and lipid-lowering drugs.

  • BMI, body mass index; CKD, chronic kidney disease; DM, diabetes mellitus; HLD, hyperlipidaemia; HR, adjusted HR; HTN, hypertension; ILD, inflammatory lung disease; IMD, Index of Multiple Deprivation; PF, pulmonary fibrosis; PS, pulmonary sarcoidosis.