Event rates per 1000 person-years according to AF status and ejection fraction group
Outcomes | Without AF | With AF | ||
Cases/person-years | IR (95% CI) | Cases/person-years | IR (95% CI) | |
All-cause mortality | ||||
HFrEF | 1167/8046.49 | 145.03 (136.83 to 153.47) | 442/3414.18 | 129.46 (117.67 to 141.80) |
HFmrEF | 282/1908.76 | 147.74 (131.00 to 165.47) | 189/1279.76 | 147.68 (127.38 to 169.47) |
HFpEF | 388/2777.88 | 139.68 (126.12 to 153.91) | 338/2247.09 | 150.42 (134.81 to 166.87) |
Composite of all-cause mortality and readmission | ||||
HFrEF | 1819/3705.35 | 490.91 (468.61 to 513.73) | 713/1676.43 | 425.31 (394.66 to 457.09) |
HFmrEF | 414/935.75 | 442.43 (400.83 to 486.05) | 289/585.46 | 493.63 (438.35 to 552.14) |
HFpEF | 596/1237.30 | 481.69 (443.79 to 521.12) | 492/1121.42 | 438.73 (400.81 to 478.33) |
CVD mortality | ||||
HFrEF | 389/8046.49 | 48.34 (43.66 to 53.26) | 141/3414.18 | 41.30 (34.76 to 48.39) |
HFmrEF | 70/1908.76 | 36.67 (28.59 to 45.75) | 45/1279.76 | 35.16 (25.65 to 46.16) |
HFpEF | 81/2777.88 | 29.16 (23.16 to 35.84) | 80/2247.09 | 35.60 (28.23 to 43.82) |
Stroke | ||||
HFrEF | 91/7823.36 | 11.63 (9.37 to 14.14) | 54/3253.85 | 16.60 (12.47 to 21.31) |
HFmrEF | 40/1818.28 | 22.00 (15.72 to 29.32) | 34/1211.74 | 28.06 (19.43 to 38.25) |
HFpEF | 35/2715.16 | 12.89 (8.98 to 17.50) | 54/2111.44 | 25.57 (19.21 to 32.83) |
AF, atrial fibrillation; CVD, cardiovascular disease; HFmrEF, heart failure with mid-range ejection fraction; HFpEF, heart failure with preserved ejection fraction; HFrEF, heart failure with reduced ejection fraction; IR, incidence rate.