| Parameter | Baseline | During GTN | p-value (paired t-test) |
|---|---|---|---|
| Mean arterial pressure (mmHg) | 78 ± 8 | 64 ± 7 | < 0.0001 |
| Heart rate (bpm) | 61 ± 7 | 69 ± 9 | 0.0002 |
| Left ventricular end diastolic volume (ml) | 166 ± 53 | 146 ± 56 | 0.001 |
| Left ventricular ejection fraction | 61 ± 3 | 66 ± 4 | 0.0008 |
| Cardiac output (L/min) | 6.52 ± 1.49 | 6.56 ± 1.41 | 0.84 |
| Cardiac work (L.mmHg/min) | 459 ± 125 | 414 ± 114 | 0.03 |
| PCr/ATP | 2.17 ± 0.24 | 1.93 ± 0.2 | 0.03 |
| Creatine kinase rate constant (s-1) | 0.16 ± 0.07 | 0.25 ± 0.09 | 0.006 |
| Creatine kinase flux (umol/g/s) | 1.76 ± 0.79 | 2.58 ± 1.07 | 0.03 |